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CAS 148319-26-0
cyclopropylbis(3-methylthiophen-2-yl)methanol
Codes: TIAG-006
Application context (from source-drug indications)
EpilepsyTiagabine HydrochlorideSeizureTiagabine HydrochlorideAnxiety disorderTiagabine HydrochlorideObstructive sleep apnoea syndromeTiagabine HydrochlorideCocaine addictionTiagabine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tiagabine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-methylthiophene-2-carbaldehyde→2-bromo-3-methylthiophene→bis(3-methylthiophen-2-yl)methanol→bis(3-methylthiophen-2-yl)methanone→bromocyclopropane→cyclopropylbis(3-methylthiophen-2-yl)methanol→2,2'-(4-bromobut-1-ene-1,1-diyl)bis(3-methylthiophene)→ethyl (R)-piperidine-3-carboxylate→ethyl (R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylate→ethyl 4-bromobutanoate
Intermediates available on this site
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