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CAS 2301968-37-4
N-[(7S,7aR,11R)-9-Iodo-1,2,3-trimethoxy-10-oxo-6,7,10,11-tetrahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide
Codes: (XVI)70274-7-b
Application context (from source-drug indications)
Coronary artery lesionColchicineMyocardial infarctionColchicineStrokeColchicine痛风性关节炎Colchicine脑出血ColchicineAtrial fibrillationColchicine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Colchicine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
[5-[(1S)-1-Amino-3-(2-ethynyl-3,4,5-trimethoxyphenyl)propyl]furan-2-yl]methanol→Acetic acid acetic anhydride→N-[(1S)-3-(2-Ethynyl-3,4,5-trimethoxyphenyl)-1-[5-(hydroxymethyl)furan-2-yl]propyl]acetamide→N-[(7S,7aR,10S,11R)-1,2,3,10-Tetramethoxy-9-oxo-6,7,8,9,10,11-hexahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide→N-[(7S,7aR,11R)-1,2,3-Trimethoxy-10-oxo-6,7,10,11-tetrahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide→N-[(7S,7aR,11R)-9-Iodo-1,2,3-trimethoxy-10-oxo-6,7,10,11-tetrahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide→Iodomethane→N-[(7S,7aR,10S,11R)-9-Iodo-1,2,3,10-tetramethoxy-6,7,10,11-tetrahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide→N-[(7S,7aR,10R,11R)-1,2,3,10-Tetramethoxy-6,7,10,11-tetrahydro-5H-7a,11-epoxybenzo[a]heptalen-7-yl]acetamide→Carbonic acid dimethyl diester→Sulfuric acid dimethyl diester
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