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CAS 4091-39-8
1-Acetyl-1-chloroethane
Codes: Josamycin-017
Application context (from source-drug indications)
Bacterial infectionJosamycin PropionateInflammatory diseaseJosamycin Propionate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Josamycin Propionate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl 6,8-di-O-benzyl-2,3,7-trideoxy-3-formyl-5-O-methyl-D-ido-octofuranoside→3-(Triphenylphosphoranylidene)butan-2-one→1-Acetyl-1-chloroethane→Methyl 6,8-di-O-benzyl-2,3,7-trideoxy-5-O-methyl-3-[(1Z)-2-methyl-3-oxobut-1-en-1-yl]-D-ido-octofuranoside→Methyl 2,3,7-trideoxy-5-O-methyl-3-(2-methyl-3-oxobutyl)-D-ido-octofuranoside→Methyl 2,3,7-trideoxy-5-O-methyl-3-(2-methyl-3-oxobutyl)-D-ido-octofuranosiduronic acid→Dimethyl 2,3,7-trideoxy-5-O-methyl-3-[(2R)-2-methyl-3-oxobutyl]-D-ido-octofuranosiduronate→(2E)-5-Hydroxyhex-2-enal→Dimethyl 2,3,7-trideoxy-3-[(2R,4E,6E,9R)-9-hydroxy-2-methyl-3-oxodeca-4,6-dien-1-yl]-5-O-methyl-D-ido-octofuranosiduronate→Methyl 2,3,7-trideoxy-3-[(2R,4E,6E,9R)-3,9-dihydroxy-2-methyldeca-4,6-dien-1-yl]-5-O-methyl-D-ido-octofuranosiduronic acid→Methyl S-phenyl 2,3,7-trideoxy-3-[(2R,4E,6E,9R)-3,9-dihydroxy-2-methyldeca-4,6-dien-1-yl]-5-O-methyl-8-thio-D-ido-octofuranosiduronate
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