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CAS 56178-02-0

3,6',7',8'-Tetramethoxy-3',4'-dihydro-2'H,4H-spiro[cyclohexa-2,5-diene-1,1'-naphthalen]-4-one

Codes: (II)70274-6-a

Application context (from source-drug indications)

Coronary artery lesionColchicineMyocardial infarctionColchicineStrokeColchicine痛风性关节炎Colchicine脑出血ColchicineAtrial fibrillationColchicine

Source drugs (routes using this intermediate)

DrugTierExpiry
ColchicineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

ColchicineOptimised routesteps: 4total yield: /
2-Methoxy-4-[3-(3,4,5-trimethoxyphenyl)propyl]phenol→3,6',7',8'-Tetramethoxy-3',4'-dihydro-2'H,4H-spiro[cyclohexa-2,5-diene-1,1'-naphthalen]-4-one→3,6',7',8'-Tetramethoxy-3',4'-dihydro-2'H-spiro[cyclohexa-2,5-diene-1,1'-naphthalen]-4-ol→4,6',7',8'-Tetramethoxy-3',4'-dihydro-2'H,5H-spiro[bicyclo[4.1.0]hept-3-ene-2,1'-naphthalen]-5-one→1,2,3,9-Tetramethoxy-6,7-dihydrobenzo[a]heptalen-10(5H)-one

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