Ampreloxetine
Tier C — Watch / tradeAmpreloxetine
Targets：NET, SERT
Indications (approved)：Multiple system atrophy, 直立性低血压, 单纯性自主神经衰竭, Parkinson's disease, Drug-related adverse effects and reactions, Attention deficit hyperactivity disorder, Fibromyalgia
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| TD-9855 | 1227056-87-2 | 4-(2-((2,4,6-trifluorophenoxy)methyl)phenyl)piperidine |
| TD-9855-001 | 1115239-19-4 | tert-butyl 4-(2-formylphenyl)piperidine-1-carboxylate |
| TD-9855-002 | 255051-62-8 | tert-butyl 4-(2-(hydroxymethyl)phenyl)piperidine-1-carboxylate |
| TD-9855-003 | 1227056-83-8 | tert-butyl 4-(2-((tosyloxy)methyl)phenyl)piperidine-1-carboxylate |
| TD-9855-004 | 2268-17-9 | 2,4,6-trifluorophenol |
| TD-9855-005 | 1227056-86-1 | tert-butyl 4-(2-((2,4,6-trifluorophenoxy)methyl)phenyl)piperidine-1-carboxylate |
Frequently asked questions
What are the approved indications of Ampreloxetine?
Approved indications include: Multiple system atrophy, 直立性低血压, 单纯性自主神经衰竭, Parkinson's disease, Drug-related adverse effects and reactions, Attention deficit hyperactivity disorder, Fibromyalgia.
When does the Ampreloxetine patent expire?
No public expiry year is available for Ampreloxetine yet; this page updates once verified.
How many synthesis routes are recorded for Ampreloxetine?
1 synthesis routes are recorded; the shortest is 4 steps with 10.2 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ampreloxetine intermediates?
All intermediates in Ampreloxetine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Ampreloxetine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-08