Firibastat
Tier C — Watch / tradeFiribastat
Targets：ENPEP
Indications (approved)：Hypertension, Heart failure, Myocardial infarction, Renal impairment, Essential hypertension
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| RB-150-001 | 39537-41-2 | (S)-2-amino-4-chlorobutanoic acid |
| RB-150-002 | 777033-03-1 | (S)-ethyl 2-amino-4-chlorobutanoate |
| RB-150-003 | 162955-18-2 | (S)-ethyl 2-((tert-butoxycarbonyl)amino)-4-chlorobutanoate |
| RB-150-004 | 162955-22-8 | sodium (S)-3-((tert-butoxycarbonyl)amino)-4-ethoxy-4-oxobutane-1-sulfonate |
| RB-150-005 | 162955-24-0 | sodium (S)-3-((tert-butoxycarbonyl)amino)-4-hydroxybutane-1-sulfonate |
| RB-150-006 | 162955-26-2 | sodium (S)-4-(acetylthio)-3-((tert-butoxycarbonyl)amino)butane-1-sulfonate |
Frequently asked questions
What are the approved indications of Firibastat?
Approved indications include: Hypertension, Heart failure, Myocardial infarction, Renal impairment, Essential hypertension.
When does the Firibastat patent expire?
No public expiry year is available for Firibastat yet; this page updates once verified.
How many synthesis routes are recorded for Firibastat?
1 synthesis routes are recorded; the shortest is 6 steps with 200 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Firibastat intermediates?
All intermediates in Firibastat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Firibastat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07