Sinapultide
Tier C — Watch / tradeSinapultide
Targets：Not applicable
Brand：Surfaxin LS, Surfaxin, AEROSURF
Indications (approved)：Acute respiratory distress syndrome, COVID-19, 新生儿呼吸窘迫综合征
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| SINA-001 | 35661-60-0 | (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine |
| SINA-002 | - | methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucinate |
| SINA-003 | - | methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucyl-L-leucinate |
| SINA-004 | - | methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucyl-L-leucyl-L-leucinate |
| SINA-005 | - | methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucyl-L-leucyl-L-leucyl-L-leucinate |
| SINA-006 | 71989-26-9 | (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid |
| SINA-007 | - | methyl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucinate |
| SINA-008 | 1417727-85-5 | N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucine |
| SINA-009 | - | methyl N6-(tert-butoxycarbonyl)-N2-N6-(tert-butoxycarbonyl)-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysinate |
| SINA-010 | - | methyl N6-(tert-butoxycarbonyl)-N2-N6-(tert-butoxycarbonyl)-N2-N6-(tert-butoxycarbonyl)-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysinate |
| SINA-011 | - | - |
| SINA-012 | - | - |
Frequently asked questions
What are the approved indications of Sinapultide?
Approved indications include: Acute respiratory distress syndrome, COVID-19, 新生儿呼吸窘迫综合征.
When does the Sinapultide patent expire?
No public expiry year is available for Sinapultide yet; this page updates once verified.
How many synthesis routes are recorded for Sinapultide?
1 synthesis routes are recorded; the shortest is 10 steps with 0.4 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Sinapultide intermediates?
All intermediates in Sinapultide routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Sinapultide intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07