Tetracaine Hydrochloride

Tier C — Watch / trade

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：Not applicable

Brand：Tonexol, TetraVisc, Tonex, Ametop, Pontocaine hydrochloride

Indications (approved)：Anaesthesia

Regional status

Approved

2016-02-29

Approved

1987-03-05

China

Approved

Japan

Approved

1959-08-01

Synthetic routes & intermediates5 routes

Originator routes × 0Optimised (non-patent) × 5Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 6 · Total yield /

Tetracaine-00162-23-7Tetracaine-002122-04-3Tetracaine-003108-01-0Tetracaine-00454288-75-4Tetracaine-00538152-22-6Tetracaine-00617599-02-9Tetracaine-00710012-47-2Tetracaine-008123-72-8Tetracaine-009109-65-9Tetracaine-01094-24-6API · Tetracaine Hydrochloride

Code	CAS No.	Intermediate
Tetracaine-001	62-23-7	4-Nitrobenzoic acid
Tetracaine-002	122-04-3	4-Nitrobenzoyl chloride
Tetracaine-003	108-01-0	N,N-Dimethylaminoethanol
Tetracaine-004	54288-75-4	2-(Dimethylamino)ethyl 4-nitrobenzoate hydrogen chloride
Tetracaine-005	38152-22-6	2-(Dimethylamino)ethyl 4-nitrobenzoate
Tetracaine-006	17599-02-9	2-(Dimethylamino)ethyl 4-aminobenzoate hydrogen chloride
Tetracaine-007	10012-47-2	4-Aminobenzoic acid 2-(dimethylamino)ethyl ester
Tetracaine-008	123-72-8	Butanal
Tetracaine-009	109-65-9	1-Bromobutane
Tetracaine-010	94-24-6	4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester

OptimisedRoute 2Steps 10 · Total yield /

Tetracaine-011555-06-6Tetracaine-0124740-24-3Tetracaine-01374-11-3Tetracaine-014586-76-5Tetracaine-015619-58-9Tetracaine-016109-73-9Tetracaine-01794-32-6Tetracaine-0182498-25-1Tetracaine-019107-07-3Tetracaine-020—Tetracaine-021124-40-3Tetracaine-009109-65-9Tetracaine-003108-01-0Tetracaine-00710012-47-2Tetracaine-01094-24-6API · Tetracaine Hydrochloride

Code	CAS No.	Intermediate
Tetracaine-011	555-06-6	4-Aminobenzoic acid sodium salt
Tetracaine-012	4740-24-3	4-(Butylamino)benzoic acid
Tetracaine-013	74-11-3 Available	p-Chlorobenzoic acid
Tetracaine-014	586-76-5 Available	4-Bromobenzoic acid
Tetracaine-015	619-58-9 Available	4-Iodobenzoic acid
Tetracaine-016	109-73-9	Butylamine
Tetracaine-017	94-32-6	4-(Butylamino)benzoic acid ethyl ester
Tetracaine-018	2498-25-1	2-(Dimethylamino)ethanol hydrochloride
Tetracaine-019	107-07-3	2-Chloroethanol
Tetracaine-020	-	4-(Butylamino)benzoic acid 2-chloroethyl ester
Tetracaine-021	124-40-3 Available	N-Methylmethanamine
Tetracaine-009	109-65-9	n-Butyl bromide
Tetracaine-003	108-01-0	N,N-Dimethylaminoethanol
Tetracaine-007	10012-47-2	4-Aminobenzoic acid 2-(dimethylamino)ethyl ester
Tetracaine-010	94-24-6	4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester

OptimisedRoute 3Steps 3 · Total yield 93.5g(Tetracaine)

Tetracaine-022150-13-0Tetracaine-008123-72-8Tetracaine-003108-01-0API · Tetracaine Hydrochloride

Code	CAS No.	Intermediate
Tetracaine-022	150-13-0	4-Aminobenzoic acid
Tetracaine-008	123-72-8	Butanal
Tetracaine-003	108-01-0	N,N-Dimethyl-2-hydroxyethylamine

OptimisedRoute 4Steps 5 · Total yield /

Tetracaine-023586-75-4Tetracaine-02438152-18-0Tetracaine-02594-09-7Tetracaine-009109-65-9Tetracaine-003108-01-0Tetracaine-016109-73-9Tetracaine-01094-24-6Tetracaine-01794-32-6Tetracaine-022150-13-0API · Tetracaine Hydrochloride

Code	CAS No.	Intermediate
Tetracaine-023	586-75-4	4-Bromobenzoyl chloride
Tetracaine-024	38152-18-0	2-(Dimethylamino)ethyl 4-bromobenzoate
Tetracaine-025	94-09-7	Ethyl 4-aminobenzoate
Tetracaine-009	109-65-9	n-Butyl bromide
Tetracaine-003	108-01-0	N,N-Dimethylaminoethanol
Tetracaine-016	109-73-9	Monobutylamine
Tetracaine-010	94-24-6	4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester
Tetracaine-017	94-32-6	4-(Butylamino)benzoic acid ethyl ester
Tetracaine-022	150-13-0	4-Aminobenzoic acid

OptimisedRoute 5Steps 3 · Total yield /

Tetracaine-02699-77-4Tetracaine-02594-09-7Tetracaine-008123-72-8Tetracaine-01794-32-6Tetracaine-003108-01-0Tetracaine-01094-24-6API · Tetracaine Hydrochloride

Code	CAS No.	Intermediate
Tetracaine-026	99-77-4	Ethyl 4-nitrobenzoate
Tetracaine-025	94-09-7	4-Aminobenzoic acid ethyl ester
Tetracaine-008	123-72-8	Butyraldehyde
Tetracaine-017	94-32-6	4-(Butylamino)benzoic acid ethyl ester
Tetracaine-003	108-01-0	N,N-Dimethyl-2-hydroxyethylamine
Tetracaine-010	94-24-6	4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester

Frequently asked questions

What are the approved indications of Tetracaine Hydrochloride?

Approved indications include: Anaesthesia.

When does the Tetracaine Hydrochloride patent expire?

No public expiry year is available for Tetracaine Hydrochloride yet; this page updates once verified.

How many synthesis routes are recorded for Tetracaine Hydrochloride?

5 synthesis routes are recorded; the shortest is 3 steps with 93.5g(Tetracaine) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Tetracaine Hydrochloride intermediates?

4 intermediate CAS of Tetracaine Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Tetracaine Hydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29