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C-188-9

Tier C — Watch / trade

C-188-9

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Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:STAT3

Indications (approved):Idiopathic pulmonary fibrosis, Hepatocellular carcinoma, Pancreatic cancer, Non-small cell lung cancer, Melanoma, Colorectal cancer, Breast cancer, Head and neck squamous cell carcinoma

Regional status

US
Phase II
2023-03-23
EU
-
China
-
Japan
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Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 143.5 g (C-188-9)
C-188-9-00198-68-0C-188-9-0025959-56-8C-188-9-003301313-43-9C-188-9-004331677-27-1C-188-9-005135-19-3API · C-188-9
CodeCAS No.Intermediate
C-188-9-00198-68-04-methoxybenzene-1-sulfonyl chloride
C-188-9-0025959-56-84-aminonaphthalen-1-ol hydrochloride
C-188-9-003301313-43-9N-(4-hydroxynaphthalen-1-yl)-4-methoxybenzenesulfonamide
C-188-9-004331677-27-1(Z)-4-methoxy-N-(4-oxonaphthalen-1(4H)-ylidene)benzenesulfonamide
C-188-9-005135-19-3naphthalen-2-ol

Frequently asked questions

What are the approved indications of C-188-9?

Approved indications include: Idiopathic pulmonary fibrosis, Hepatocellular carcinoma, Pancreatic cancer, Non-small cell lung cancer, Melanoma, Colorectal cancer, Breast cancer, Head and neck squamous cell carcinoma.

When does the C-188-9 patent expire?

No public expiry year is available for C-188-9 yet; this page updates once verified.

How many synthesis routes are recorded for C-188-9?

1 synthesis routes are recorded; the shortest is 3 steps with 143.5 g (C-188-9) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy C-188-9 intermediates?

All intermediates in C-188-9 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for C-188-9 intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-03