Avatrombopag Maleate
Tier C — Watch / tradeAvatrombopag Maleate · all drugs expiring in 2030 →
Targets：TpoR
Brand：Doptelet, DOPTELET
Indications (approved)：Thrombocytopenia, Immune thrombocytopenic purpura, Liver disease
Regional status
Factories producing this API1
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
1 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AVAT-001 | 34730-20-6Available | 1-(4-chlorothiophen-2-yl)ethanone |
| AVAT-002 | 677007-73-7Available | 2-bromo-1-(4-chlorothiophen-2-yl)ethanone |
| AVAT-003 | 62-56-6Available | thiourea |
| AVAT-004 | 570407-10-2Available | 4-(4-chlorothiophen-2-yl)thiazol-2-amine |
| AVAT-005 | 17766-28-8Available | 1-cyclohexylpiperazine |
| AVAT-006 | 570407-42-0Available | 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine |
| AVAT-007 | 41667-95-2Available | 5,6-dichloronicotinic acid |
| AVAT-008 | 570403-04-2Available | 5,6-dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide |
| AVAT-009 | 1126-09-6Available | ethyl piperidine-4-carboxylate |
| AVAT-010 | 570403-14-4Available | ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate |
| AVAT-011 | 110-16-7Available | maleic acid |
Frequently asked questions
What are the approved indications of Avatrombopag Maleate?
Approved indications include: Thrombocytopenia, Immune thrombocytopenic purpura, Liver disease.
When does the Avatrombopag Maleate patent expire?
Based on public sources, the Avatrombopag Maleate patent expires in 2030.
How many synthesis routes are recorded for Avatrombopag Maleate?
1 synthesis routes are recorded; the shortest is 7 steps with 20 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Avatrombopag Maleate intermediates?
11 intermediate CAS of Avatrombopag Maleate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Avatrombopag Maleate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29