Levosimendan
Tier C — Watch / tradeLevosimendan
Targets：Potassium channel, VGKCs, PDE3, Troponin, cardiac muscle
Brand：Simdax
Indications (approved)：Heart failure
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| LEVOS-001 | 36725-28-7Available | 6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one |
| LEVOS-002 | 101328-85-2Available | (R)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one |
| LEVOS-003 | 109-77-3Available | malononitrile |
Frequently asked questions
What are the approved indications of Levosimendan?
Approved indications include: Heart failure.
When does the Levosimendan patent expire?
No public expiry year is available for Levosimendan yet; this page updates once verified.
How many synthesis routes are recorded for Levosimendan?
1 synthesis routes are recorded; the shortest is 2 steps with 6.8 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Levosimendan intermediates?
3 intermediate CAS of Levosimendan are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Levosimendan intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29