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Leniolisib phosphate

Tier C — Watch / trade

Leniolisib phosphate

Novartis
Originator
2023
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PI3Kδ

Brand:JOENJA

Indications (approved):原发性免疫缺陷疾病, PI3Kδ过度活化综合征

Regional status

US
Approved
2023-03-24
EU
Approved
2026-05-21
China
-
Japan
Approved
2026-03-23

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield 9.42 g
LENI-001147081-44-5LENI-002914612-23-0LENI-0031354691-71-6LENI-0041354691-72-7LENI-0051214377-42-0LENI-0061354691-73-8LENI-007121643-44-5API · Leniolisib phosphate
CodeCAS No.Intermediate
LENI-001147081-44-5(S)-tert-butyl 3-aminopyrrolidine-1-carboxylate
LENI-002914612-23-06-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
LENI-0031354691-71-6tert-butyl (S)-3-((6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate
LENI-0041354691-72-7tert-butyl (S)-3-((5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate
LENI-0051214377-42-05-bromo-2-methoxy-3-(trifluoromethyl)pyridine
LENI-0061354691-73-8tert-butyl (S)-3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate
LENI-007121643-44-52-methoxy-3-(trifluoromethyl)pyridine

Frequently asked questions

What are the approved indications of Leniolisib phosphate?

Approved indications include: 原发性免疫缺陷疾病, PI3Kδ过度活化综合征.

When does the Leniolisib phosphate patent expire?

No public expiry year is available for Leniolisib phosphate yet; this page updates once verified.

How many synthesis routes are recorded for Leniolisib phosphate?

1 synthesis routes are recorded; the shortest is 5 steps with 9.42 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Leniolisib phosphate intermediates?

All intermediates in Leniolisib phosphate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Leniolisib phosphate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29