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Ceftazidime/Tazobactam Sodium
Tier C — Watch / tradeCeftazidime/Tazobactam Sodium
Xiangbei Welman Pharmaceutical Co., Ltd.
Originator
2010
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type
Targets：PBPs, Beta Lactamase
Indications (approved)：Bacterial infection
Regional status
US
-
EU
-
China
Approved
2010-03-15
Japan
-
Factories producing this API9
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
9 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates24 routes
Originator routes × 1Optimised (non-patent) × 22Process routes × 1
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
OriginatorRoute 1Steps 10 · Total yield /
Ceftazidime-001141-97-9Ceftazidime-002109-95-5Ceftazidime-0031516-08-1,64-17-5Ceftazidime-0045408-04-8Ceftazidime-00562-56-6Ceftazidime-00660845-81-0Ceftazidime-00766338-99-6Ceftazidime-00823877-12-5Ceftazidime-00968672-65-1Ceftazidime-01068672-66-2Ceftazidime-011957-68-6Ceftazidime-012127664-87-3Ceftazidime-01373443-60-4Ceftazidime-014110-86-1API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-001 | 141-97-9Available | ethyl 3-oxobutanoate |
| Ceftazidime-002 | 109-95-5 | Ethyl nitrite |
| Ceftazidime-003 | 1516-08-1,64-17-5 | Non-denatured ethanol |
| Ceftazidime-004 | 5408-04-8 | ethyl (E)-2-(hydroxyimino)-3-oxobutanoate |
| Ceftazidime-005 | 62-56-6Available | thiourea |
| Ceftazidime-006 | 60845-81-0 | ethyl (Z)-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetate |
| Ceftazidime-007 | 66338-99-6 | Ethyl (2Z)-(hydroxyimino)[2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl]acetate |
| Ceftazidime-008 | 23877-12-5 | tert-Butyl 2-bromo-2-methylpropionate |
| Ceftazidime-009 | 68672-65-1 | tert-Butyl 2-[[(Z)-(2-ethoxy-2-oxo-1-[2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl]ethylidene)amino]oxy]-2-methylpropanoate |
| Ceftazidime-010 | 68672-66-2 | (2Z)-[[(1-tert-Butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino][2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl]acetic acid |
| Ceftazidime-011 | 957-68-6 | (6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Ceftazidime-012 | 127664-87-3 | (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]-2-[2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Ceftazidime-013 | 73443-60-4 | (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[[(2-carboxypropan-2-yl)oxy]imino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Ceftazidime-014 | 110-86-1 | pyridine |
OptimisedRoute 2Steps 11 · Total yield /
Ceftazidime-011957-68-6Ceftazidime-01531461-04-8Ceftazidime-016106134-67-2Ceftazidime-014110-86-1Ceftazidime-01798445-42-2Ceftazidime-01896752-43-1Ceftazidime-0191040394-00-0Ceftazidime-02089604-92-2Ceftazidime-021102772-66-7API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-011 | 957-68-6 | (6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Ceftazidime-015 | 31461-04-8 | Trimethylsilyl 7-(trimethylsilylamino)cephalosporanate |
| Ceftazidime-016 | 106134-67-2 | Trimethylsilyl (6R,7R)-3-(iodomethyl)-8-oxo-7-[(trimethylsilyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| Ceftazidime-014 | 110-86-1 | Pyridine |
| Ceftazidime-017 | 98445-42-2 | 1-[[(6R,7R)-8-Oxo-7-[(trimethylsilyl)amino]-2-[[(trimethylsilyl)oxy]carbonyl]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridin-1-ium iodide |
| Ceftazidime-018 | 96752-43-1 | (6R,7R)-7-Amino-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride |
| Ceftazidime-019 | 1040394-00-0 | 2-[[(Z)-[1-(2-Amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid |
| Ceftazidime-020 | 89604-92-2 | tert-Butyl 2-[[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene]amino]oxy]-2-methylpropanoate |
| Ceftazidime-021 | 102772-66-7 | (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetyl]amino]-8-oxo-3-[(pyridin-1-ium-1-yl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylat e |
OptimisedRoute 3Steps 1 · Total yield /
Ceftazidime-02089604-92-2Ceftazidime-02286299-46-9Ceftazidime-023120-78-5Ceftazidime-02486299-47-0API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-020 | 89604-92-2 | tert-Butyl 2-[[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene]amino]oxy]-2-methylpropanoate |
| Ceftazidime-022 | 86299-46-9 | tert-Butyl 2-([(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-ethoxy-2-oxoethylidene]amino]oxy)-2-methylpropanoate |
| Ceftazidime-023 | 120-78-5 | 2-(1,3-Benzothiazol-2-yldisulfanyl)-1,3-benzothiazole |
| Ceftazidime-024 | 86299-47-0 | (2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid |
OptimisedRoute 4Steps 6 · Total yield /
Ceftazidime-02579-31-2Ceftazidime-0262052-01-9Ceftazidime-00823877-12-5Ceftazidime-02760845-81-0Ceftazidime-02286299-46-9Ceftazidime-02486299-47-0Ceftazidime-028354808-44-9Ceftazidime-029100988-63-4API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-025 | 79-31-2Available | 2-Methylpropionic acid |
| Ceftazidime-026 | 2052-01-9 | 2-Bromo-2-methylpropanoic acid |
| Ceftazidime-008 | 23877-12-5 | t-Butyl 2-bromo isobutyrate |
| Ceftazidime-027 | 60845-81-0 | 2(Z)-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid ethyl ester |
| Ceftazidime-022 | 86299-46-9 | tert-Butyl 2-([(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-ethoxy-2-oxoethylidene]amino]oxy)-2-methylpropanoate |
| Ceftazidime-024 | 86299-47-0 | (2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid |
| Ceftazidime-028 | 354808-44-9 | 2-([[(1Z)-1-(2-Amino-1,3-thiazol-4-yl)-2-chloro-2-oxoethylidene]amino]oxy)-2-methylpropanoic acid hydrochloride |
| Ceftazidime-029 | 100988-63-4 | (6R,7R)-7-Amino-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydroiodide |
OptimisedRoute 5Steps 2 · Total yield /
Ceftazidime-030149-30-4Ceftazidime-02089604-92-2Ceftazidime-023120-78-5Ceftazidime-02286299-46-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-030 | 149-30-4Available | 2-Mercaptobenzothiazole |
| Ceftazidime-020 | 89604-92-2 | tert-Butyl 2-[[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene]amino]oxy]-2-methylpropanoate |
| Ceftazidime-023 | 120-78-5 | 2-(1,3-Benzothiazol-2-yldisulfanyl)-1,3-benzothiazole |
| Ceftazidime-022 | 86299-46-9 | tert-Butyl 2-([(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-ethoxy-2-oxoethylidene]amino]oxy)-2-methylpropanoate |
OptimisedRoute 6Steps 3 · Total yield /
Ceftazidime-036619-60-3Ceftazidime-031—Ceftazidime-033128378-10-9Ceftazidime-0341879943-41-5Ceftazidime-035123-30-8Ceftazidime-02486299-47-0Ceftazidime-014110-86-1Ceftazidime-032113479-65-5API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-036 | 619-60-3 | 4-(Dimethylamino)phenol |
| Ceftazidime-031 | - | tert-Butyl (5Z)-5-(2-amino-1,3-thiazol-4-yl)-8,8-dimethyl-4-oxo-3,7-dioxa-2-thia-6-azanon-5-en-9-oate 2,2-dioxide |
| Ceftazidime-033 | 128378-10-9 | 4-Methoxybenzyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetyl]amino]-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| Ceftazidime-034 | 1879943-41-5 | 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetyl]amino]-2-[[(4-methoxybenzyl)oxy]carbonyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride |
| Ceftazidime-035 | 123-30-8Available | 4-Hydroxyaniline |
| Ceftazidime-024 | 86299-47-0 | (2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid |
| Ceftazidime-014 | 110-86-1 | Pyridine |
| Ceftazidime-032 | 113479-65-5 | 4-Methoxybenzyl (6R,7R)-7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride |
OptimisedRoute 7Steps 1 · Total yield /
Ceftazidime-023120-78-5Ceftazidime-038—Ceftazidime-037102507-85-7API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-023 | 120-78-5 | Bis(benzothiazol-2-yl)disulfide |
| Ceftazidime-038 | - | S-1,3-Benzothiazol-2-yl 2-[[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene]amino]oxy]-2-methylpropanethioate |
| Ceftazidime-037 | 102507-85-7 | 2-{[(Z)-[(2-amino-1,3-thiazol-4-yl)(carboxy)methylidene]amino]oxy}-2-methylpropanoic acid |
OptimisedRoute 8Steps 2 · Total yield /
Ceftazidime-03998445-42-2Ceftazidime-028354808-44-9Ceftazidime-0401809092-47-4API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-039 | 98445-42-2 | 1-[[(6R,7R)-8-Oxo-7-[(trimethylsilyl)amino]-2-[[(trimethylsilyl)oxy]carbonyl]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridin-1-ium iodide |
| Ceftazidime-028 | 354808-44-9 | 2-([[(1Z)-1-(2-Amino-1,3-thiazol-4-yl)-2-chloro-2-oxoethylidene]amino]oxy)-2-methylpropanoic acid hydrochloride |
| Ceftazidime-040 | 1809092-47-4 | 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[[(2-carboxypropan-2-yl)oxy]imino]acetyl]amino]-8-oxo-2-[[(trimethylsilyl)oxy]carbonyl]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridin-1-ium iodide |
OptimisedRoute 9Steps 4 · Total yield /
Ceftazidime-02486299-47-0Ceftazidime-029100988-63-4Ceftazidime-00660845-81-0Ceftazidime-00823877-12-5Ceftazidime-041—Ceftazidime-044—Ceftazidime-021102772-66-7Ceftazidime-042—Ceftazidime-043—API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-024 | 86299-47-0 | (2Z)-(2-Amino-1,3-thiazol-4-yl)[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetic acid |
| Ceftazidime-029 | 100988-63-4 | (6R,7R)-7-Amino-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydroiodide |
| Ceftazidime-006 | 60845-81-0 | 2(Z)-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid ethyl ester |
| Ceftazidime-008 | 23877-12-5 | tert-Butyl 2-bromo-2-methylpropionate<-fgf->2-Bromo-2-methylpropionic acid tert-butyl ester |
| Ceftazidime-041 | - | Sodium (2Z)-(2-amino-1,3-thiazol-4-yl)(hydroxyimino)acetate |
| Ceftazidime-044 | - | tert-Butyl 2-[[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(4-methylphenyl)sulfonyl]oxy]-2-oxoethylidene]amino]oxy]-2-methylpropanoate |
| Ceftazidime-021 | 102772-66-7 | (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino]acetyl]amino]-8-oxo-3-[(pyridin-1-ium-1-yl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylat e |
| Ceftazidime-042 | - | Potassium (2Z)-(2-amino-1,3-thiazol-4-yl)(hydroxyimino)acetate |
| Ceftazidime-043 | - | Lithium (2Z)-(2-amino-1,3-thiazol-4-yl)(hydroxyimino)acetate |
OptimisedRoute 10Steps 1 · Total yield /
Ceftazidime-04518820-82-1Ceftazidime-014110-86-1API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-045 | 18820-82-1 | Pyridine hydrobromide |
| Ceftazidime-014 | 110-86-1 | Pyridine |
OptimisedRoute 11Steps 1 · Total yield /
Ceftazidime-04666338-95-2Ceftazidime-04762-56-6Ceftazidime-04864513-00-4API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Ceftazidime-046 | 66338-95-2 | Ethyl (2Z)-4-chloro-2-(hydroxyimino)-3-oxobutanoate |
| Ceftazidime-047 | 62-56-6Available | Thiocarbamide |
| Ceftazidime-048 | 64513-00-4 | Ethyl (2E)-(2-amino-1,3-thiazol-4-yl)(hydroxyimino)acetate |
OptimisedRoute 1Steps 8 · Total yield 181.68g(Tazobactam (Free))
Tazobactam Sodium-00187579-78-0Tazobactam Sodium-002149-30-4Tazobactam Sodium-00387579-79-1Tazobactam Sodium-00485573-73-5Tazobactam Sodium-00589051-47-8Tazobactam Sodium-00689051-49-0Tazobactam Sodium-0071066-54-2Tazobactam Sodium-008—Tazobactam Sodium-00989789-07-1Tazobactam Sodium-01074-86-2Tazobactam Sodium-011108-05-4Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-001 | 87579-78-0Available | (2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide |
| Tazobactam Sodium-002 | 149-30-4Available | 1,3-Benzothiazole-2-thiol |
| Tazobactam Sodium-003 | 87579-79-1Available | (2R)-2-[(2R)-2-[(Benzothiazol-2-yl)dithio]-4-oxoazetidin-1-yl]-3-methyl-3-butenoic acid benzhydryl ester |
| Tazobactam Sodium-004 | 85573-73-5Available | (2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-005 | 89051-47-8Available | Benzhydryl (2S,3S,5R)-3-(azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-006 | 89051-49-0Available | Benzhydryl (2S,3S,5R)-3-(azidomethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-007 | 1066-54-2Available | 1-Trimethylsilylethyne |
| Tazobactam Sodium-008 | - | Benzhydryl 2a-methyl-2beta-(4-trimethylsilyl-1,2,3-triazol-1 ylmethyl)penam-3a-carboxylate-1,1-dioxide |
| Tazobactam Sodium-009 | 89789-07-1Available | Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Tazobactam Sodium-010 | 74-86-2Available | Acetylene |
| Tazobactam Sodium-011 | 108-05-4Available | 1-Acetoxyethylene |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
OptimisedRoute 3Steps 14 · Total yield 17g(Tazobactam Sodium-029)
Tazobactam Sodium-021551-16-6Tazobactam Sodium-02224158-88-1Tazobactam Sodium-02375527-84-3Tazobactam Sodium-024113891-01-3Tazobactam Sodium-00187579-78-0Tazobactam Sodium-02569126-86-9Tazobactam Sodium-02613257-88-0Tazobactam Sodium-027288-36-8Tazobactam Sodium-028120241-79-4Tazobactam Sodium-020125949-72-6Tazobactam Sodium-029—Tazobactam Sodium-03079703-02-9Tazobactam Sodium-0315350-57-2Tazobactam Sodium-03287-53-6Tazobactam Sodium-03379702-81-1Tazobactam Sodium-03473968-83-9Tazobactam Sodium-002149-30-4Tazobactam Sodium-00387579-79-1Tazobactam Sodium-03572118-49-1Tazobactam Sodium-03689051-48-9Tazobactam Sodium-00485573-73-5Tazobactam Sodium-037—API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-021 | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| Tazobactam Sodium-022 | 24158-88-1Available | (2S,5R)-6,6-Dibromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-023 | 75527-84-3Available | Diphenylmethyl (2S,5R)-6,6-dibromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-024 | 113891-01-3Available | Diphenylmethyl (2S,5R)-6,6-dibromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
| Tazobactam Sodium-001 | 87579-78-0Available | (2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide |
| Tazobactam Sodium-025 | 69126-86-9Available | Methyl (2S,5R)-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-026 | 13257-88-0Available | 1-(Trimethylsilyl)-1,2,3-triazole |
| Tazobactam Sodium-027 | 288-36-8Available | 1,2,3-Triazole |
| Tazobactam Sodium-028 | 120241-79-4Available | 3-(1,2,3-Triazol-4-yl)pyridine |
| Tazobactam Sodium-020 | 125949-72-6Available | (2S,3S,5R)-2-Methyl-2-(1H-1,2,3-triazol-1-ylmethyl)penam-3-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-029 | - | Methyl (2S,3S,5R)-3-methyl-7-oxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-030 | 79703-02-9Available | (2S,4R,6S)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide |
| Tazobactam Sodium-031 | 5350-57-2Available | (Diphenylmethylidene)hydrazine |
| Tazobactam Sodium-032 | 87-53-6Available | (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-033 | 79702-81-1Available | (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide |
| Tazobactam Sodium-034 | 73968-83-9Available | Benzhydryl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-002 | 149-30-4Available | 1,3-Benzothiazole-2-thiol |
| Tazobactam Sodium-003 | 87579-79-1Available | (2R)-2-[(2R)-2-[(Benzothiazol-2-yl)dithio]-4-oxoazetidin-1-yl]-3-methyl-3-butenoic acid benzhydryl ester |
| Tazobactam Sodium-035 | 72118-49-1Available | Methyl (2R)-2-[(2R)-2-[(1,3-benzothiazol-2-yl)disulfanyl]-4-oxoazetidin-1-yl]-3-methylbut-3-enoate |
| Tazobactam Sodium-036 | 89051-48-9Available | Diphenylmethyl (2S,3R,5R)-3-(bromomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-004 | 85573-73-5Available | (2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-037 | - | Methyl (2S,3R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
OptimisedRoute 4Steps 7 · Total yield 5g(Tazobactam (Free))
Tazobactam Sodium-027288-36-8Tazobactam Sodium-038—Tazobactam Sodium-020125949-72-6Tazobactam Sodium-029—Tazobactam Sodium-00989789-07-1Tazobactam Sodium-039—Tazobactam Sodium-01289786-04-9Tazobactam Sodium-03689051-48-9Tazobactam Sodium-040—Tazobactam Sodium-0412775432-22-7Tazobactam Sodium-042—API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-027 | 288-36-8Available | 1,2,3-Triazole |
| Tazobactam Sodium-038 | - | Silver(1+) 1,2,3-triazol-1-ide |
| Tazobactam Sodium-020 | 125949-72-6Available | (2S,3S,5R)-2-Methyl-2-(1H-1,2,3-triazol-1-ylmethyl)penam-3-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-029 | - | Methyl (2S,3S,5R)-3-methyl-7-oxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-009 | 89789-07-1Available | Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Tazobactam Sodium-039 | - | Methyl (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-036 | 89051-48-9Available | Diphenylmethyl (2S,3R,5R)-3-(bromomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-040 | - | Diphenylmethyl (2S,3R,4R,5R)-3-(bromomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
| Tazobactam Sodium-041 | 2775432-22-7Available | (Z)-Ethene-1,2-diamine hydrogen chloride |
| Tazobactam Sodium-042 | - | Diphenylmethyl (2S,3S,4R,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
OptimisedRoute 5Steps 15 · Total yield 4.6g(Tazobactam (Free))
Tazobactam Sodium-021551-16-6Tazobactam Sodium-04324138-28-1Tazobactam Sodium-03079703-02-9Tazobactam Sodium-0315350-57-2Tazobactam Sodium-044883-40-9Tazobactam Sodium-04580353-26-0Tazobactam Sodium-04674189-25-6Tazobactam Sodium-00187579-78-0Tazobactam Sodium-002149-30-4Tazobactam Sodium-00387579-79-1Tazobactam Sodium-00485573-73-5Tazobactam Sodium-047—Tazobactam Sodium-048—Tazobactam Sodium-00689051-49-0Tazobactam Sodium-049104893-87-0Tazobactam Sodium-00589051-47-8Tazobactam Sodium-01074-86-2Tazobactam Sodium-00989789-07-1Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-021 | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| Tazobactam Sodium-043 | 24138-28-1Available | (2S,5R,6S)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-030 | 79703-02-9Available | (2S,4R,6S)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide |
| Tazobactam Sodium-031 | 5350-57-2Available | (Diphenylmethylidene)hydrazine |
| Tazobactam Sodium-044 | 883-40-9Available | [Diazo(phenyl)methyl]benzene |
| Tazobactam Sodium-045 | 80353-26-0Available | (2S,5R,6S)-Benzhydryl 6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
| Tazobactam Sodium-046 | 74189-25-6Available | Diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-001 | 87579-78-0Available | (2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide |
| Tazobactam Sodium-002 | 149-30-4Available | 1,3-Benzothiazole-2-thiol |
| Tazobactam Sodium-003 | 87579-79-1Available | (2R)-2-[(2R)-2-[(Benzothiazol-2-yl)dithio]-4-oxoazetidin-1-yl]-3-methyl-3-butenoic acid benzhydryl ester |
| Tazobactam Sodium-004 | 85573-73-5Available | (2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-047 | - | Diphenylmethyl (2S,3R,4R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
| Tazobactam Sodium-048 | - | Diphenylmethyl (2S,3S,4R,5R)-3-(azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide |
| Tazobactam Sodium-006 | 89051-49-0Available | Benzhydryl (2S,3S,5R)-3-(azidomethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-049 | 104893-87-0Available | Diphenylmethyl (2R,3S,6R)-3-azido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate |
| Tazobactam Sodium-005 | 89051-47-8Available | Benzhydryl (2S,3S,5R)-3-(azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-010 | 74-86-2Available | Acetylene |
| Tazobactam Sodium-009 | 89789-07-1Available | Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
OptimisedRoute 6Steps 3 · Total yield 27.8g(Tazobactam Sodium-009)
Tazobactam Sodium-00485573-73-5Tazobactam Sodium-00689051-49-0Tazobactam Sodium-00989789-07-1Tazobactam Sodium-05085573-74-6Tazobactam Sodium-027288-36-8API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-004 | 85573-73-5Available | (2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-006 | 89051-49-0Available | Benzhydryl (2S,3S,5R)-3-(azidomethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-009 | 89789-07-1Available | Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Tazobactam Sodium-050 | 85573-74-6Available | Diphenylmethyl (2S,3R,5R)-3-(chloromethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-027 | 288-36-8Available | 1,2,3-Triazole |
OptimisedRoute 7Steps 5 · Total yield 167g(Tazobactam Sodium-001)
Tazobactam Sodium-021551-16-6Tazobactam Sodium-0315350-57-2Tazobactam Sodium-00187579-78-0Tazobactam Sodium-05199395-86-5Tazobactam Sodium-052134866-13-0Tazobactam Sodium-053134866-14-1API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-021 | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| Tazobactam Sodium-031 | 5350-57-2Available | (Diphenylmethylidene)hydrazine |
| Tazobactam Sodium-001 | 87579-78-0Available | (2S,5R)-2beta-[(Benzhydryloxy)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4-oxide |
| Tazobactam Sodium-051 | 99395-86-5Available | Diphenylmethyl (2S,4R,5R,6R)-6-amino-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-052 | 134866-13-0Available | (2S,5R,6R)-6-[(tert-Butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-053 | 134866-14-1Available | Diphenylmethyl (2S,5R,6R)-6-[(tert-butoxycarbonyl)amino]-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
OptimisedRoute 8Steps 1 · Total yield /
Tazobactam Sodium-05425232-41-1API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-054 | 25232-41-1Available | alpha,omega-Dimethylpoly[1-(pyridin-4-yl)ethane-1,2-diyl] |
OptimisedRoute 9Steps 1 · Total yield 12.0916g(Tazobactam (Free))
Tazobactam Sodium-055117030-11-2Tazobactam Sodium-015471-25-0Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-055 | 117030-11-2Available | (2S,3S,5R)-3-(Azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide |
| Tazobactam Sodium-015 | 471-25-0Available | 2-Propynoic acid |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
OptimisedRoute 10Steps 2 · Total yield /
Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
OptimisedRoute 11Steps 9 · Total yield 7.4g(Tazobactam (Free))
Tazobactam Sodium-03079703-02-9Tazobactam Sodium-05674367-78-5Tazobactam Sodium-057618-85-9Tazobactam Sodium-05880078-08-6Tazobactam Sodium-059—Tazobactam Sodium-06076911-22-3Tazobactam Sodium-061—Tazobactam Sodium-002149-30-4Tazobactam Sodium-0622375589-54-9Tazobactam Sodium-063—Tazobactam Sodium-0642375589-55-0Tazobactam Sodium-065—Tazobactam Sodium-0662375589-56-1Tazobactam Sodium-0672376815-36-8Tazobactam Sodium-068117030-09-8Tazobactam Sodium-069—Tazobactam Sodium-01074-86-2Tazobactam Sodium-070117030-07-6Tazobactam Sodium-0712376815-35-7Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-030 | 79703-02-9Available | (2S,4R,6S)-6-Bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide |
| Tazobactam Sodium-056 | 74367-78-5Available | 1-(Chloromethyl)-3,5-dinitrobenzene |
| Tazobactam Sodium-057 | 618-85-9Available | 1-Methyl-3,5-dinitrobenzene |
| Tazobactam Sodium-058 | 80078-08-6Available | Benzyl (2S,4R,5R,6S)-6-bromo-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-059 | - | (3,5-Dinitrophenyl)methyl (2S,4R,5R,6S)-6-bromo-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-060 | 76911-22-3Available | Benzyl (2S,4R,5R)-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-061 | - | (3,5-Dinitrophenyl)methyl (2S,4R,5R)-3,3-dimethyl-4,7-dioxo-4lambda4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-002 | 149-30-4Available | 1,3-Benzothiazole-2-thiol |
| Tazobactam Sodium-062 | 2375589-54-9Available | Benzyl (2R)-2-[(2R)-2-[(1,3-benzothiazol-2-yl)disulfanyl]-4-oxoazetidin-1-yl]-3-methylbut-3-enoate |
| Tazobactam Sodium-063 | - | (3,5-Dinitrophenyl)methyl (2R)-2-[(2R)-2-[(1,3-benzothiazol-2-yl)disulfanyl]-4-oxoazetidin-1-yl]-3-methylbut-3-enoate |
| Tazobactam Sodium-064 | 2375589-55-0Available | Benzyl (2S,3R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-065 | - | (3,5-Dinitrophenyl)methyl (2S,3R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-066 | 2375589-56-1Available | Benzyl (2S,3S,5R)-3-(azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-067 | 2376815-36-8Available | (3,5-Dinitrophenyl)methyl (2S,3S,5R)-3-(azidomethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-068 | 117030-09-8Available | Benzyl (2S,3S,5R)-3-(azidomethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-069 | - | (3,5-Dinitrophenyl)methyl (2S,3S,5R)-3-(azidomethyl)-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-010 | 74-86-2Available | Acetylene |
| Tazobactam Sodium-070 | 117030-07-6Available | Benzyl (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-071 | 2376815-35-7Available | (3,5-Dinitrophenyl)methyl (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
OptimisedRoute 12Steps 3 · Total yield 43.6g(Tazobactam Sodium-027)
Tazobactam Sodium-013107-22-2Tazobactam Sodium-0725470-11-1Tazobactam Sodium-07317016-13-6Tazobactam Sodium-017584-14-5Tazobactam Sodium-027288-36-8API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-013 | 107-22-2Available | Ethanedial |
| Tazobactam Sodium-072 | 5470-11-1Available | Hydroxylamine hydrochloric acid salt |
| Tazobactam Sodium-073 | 17016-13-6Available | N,N'-(1E,2E)-Ethane-1,2-diylidenedihydroxylamine |
| Tazobactam Sodium-017 | 584-14-5Available | 1H-1,2,3-Triazol-1-amine |
| Tazobactam Sodium-027 | 288-36-8Available | 1,2,3-Triazole |
OptimisedRoute 13Steps 5 · Total yield 25.72g(Tazobactam (Free))
Tazobactam Sodium-03379702-81-1Tazobactam Sodium-074—Tazobactam Sodium-075—Tazobactam Sodium-076—Tazobactam Sodium-027288-36-8Tazobactam Sodium-077132182-82-2Tazobactam Sodium-01289786-04-9API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-033 | 79702-81-1Available | (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide |
| Tazobactam Sodium-074 | - | (2S,5R)-3-[(Acetyloxy)methyl]-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-075 | - | (2S,5R)-3-(Hydroxymethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-076 | - | (2S,5R)-3-[[(Methanesulfonyl)oxy]methyl]-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-027 | 288-36-8Available | 1,2,3-Triazole |
| Tazobactam Sodium-077 | 132182-82-2Available | (2S,3S,5R)-3-Methyl-7-oxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Tazobactam Sodium-012 | 89786-04-9Available | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
ProcessRoute 2Steps 7 · Total yield 1046.36g(Tazobactam Sodium-009)
Tazobactam Sodium-00485573-73-5Tazobactam Sodium-00989789-07-1Tazobactam Sodium-013107-22-2Tazobactam Sodium-014302-01-2Tazobactam Sodium-0167677-13-6Tazobactam Sodium-017584-14-5Tazobactam Sodium-018—Tazobactam Sodium-019—Tazobactam Sodium-015471-25-0Tazobactam Sodium-020125949-72-6API · Ceftazidime/Tazobactam Sodium
| Code | CAS No. | Intermediate |
|---|---|---|
| Tazobactam Sodium-004 | 85573-73-5Available | (2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester |
| Tazobactam Sodium-009 | 89789-07-1Available | Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Tazobactam Sodium-013 | 107-22-2Available | Ethanedial |
| Tazobactam Sodium-014 | 302-01-2Available | Diamine |
| Tazobactam Sodium-016 | 7677-13-6Available | 1,1'-(Ethane-1,2-diylidene)dihydrazine |
| Tazobactam Sodium-017 | 584-14-5Available | 1H-1,2,3-Triazol-1-amine |
| Tazobactam Sodium-018 | - | 3-Amino-1-([(2S,3S,5R)-2-[(diphenylmethoxy)carbonyl]-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl)-1H-1,2,3-triazol-3-ium chloride |
| Tazobactam Sodium-019 | - | 3-Amino-1-([(2S,3S,5R)-2-[(diphenylmethoxy)carbonyl]-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl)-1H-1,2,3-triazol-3-ium chloride |
| Tazobactam Sodium-015 | 471-25-0Available | 2-Propynoic acid |
| Tazobactam Sodium-020 | 125949-72-6Available | (2S,3S,5R)-2-Methyl-2-(1H-1,2,3-triazol-1-ylmethyl)penam-3-carboxylic acid diphenylmethyl ester |
Frequently asked questions
What are the approved indications of Ceftazidime/Tazobactam Sodium?
Approved indications include: Bacterial infection.
When does the Ceftazidime/Tazobactam Sodium patent expire?
No public expiry year is available for Ceftazidime/Tazobactam Sodium yet; this page updates once verified.
How many synthesis routes are recorded for Ceftazidime/Tazobactam Sodium?
24 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ceftazidime/Tazobactam Sodium intermediates?
62 intermediate CAS of Ceftazidime/Tazobactam Sodium are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Ceftazidime/Tazobactam Sodium intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29