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Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
Tier C — Watch / tradeDextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
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Originator
2006
First approval
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Expiry (public)
No sales data
Peak sales
Small molecule
Type
Targets：Updating
Regional status
US
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EU
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China
Approved
2006-03-02
Japan
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Factories producing this API21
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
21 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates5 routes
Originator routes × 2Optimised (non-patent) × 3Process routes × 0
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
OriginatorRoute 1Steps 11 · Total yield 685 g
Conteltinib-001873-83-6Conteltinib-002107-20-0Conteltinib-00339929-79-8Conteltinib-00416372-12-6Conteltinib-0052139336-89-1Conteltinib-0061312162-73-4Conteltinib-00779099-07-3Conteltinib-008109-01-3Conteltinib-009190964-91-1Conteltinib-01053617-36-0Conteltinib-011448-19-1Conteltinib-012761440-65-7Conteltinib-013761440-75-9Conteltinib-014109-86-4Conteltinib-0152139336-90-4Conteltinib-016761435-31-8Conteltinib-0172139336-91-5API · Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
| Code | CAS No. | Intermediate |
|---|---|---|
| Conteltinib-001 | 873-83-6 | 6-aminopyrimidine-2,4(1H,3H)-dione |
| Conteltinib-002 | 107-20-0 | 2-chloroacetaldehyde |
| Conteltinib-003 | 39929-79-8 | 7H-pyrrolo[2,3-d]pyrimidine-2,4-diol |
| Conteltinib-004 | 16372-12-6 | 6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine-2,4-diol |
| Conteltinib-005 | 2139336-89-1 | 2,4-dichloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine |
| Conteltinib-006 | 1312162-73-4 | 2,4-dichloro-7-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine |
| Conteltinib-007 | 79099-07-3Available | tert-butyl 4-oxopiperidine-1-carboxylate |
| Conteltinib-008 | 109-01-3Available | 1-methylpiperazine |
| Conteltinib-009 | 190964-91-1 | tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate |
| Conteltinib-010 | 53617-36-0 | 1-methyl-4-(piperidin-4-yl)piperazine |
| Conteltinib-011 | 448-19-1 | 4-fluoro-2-methoxy-1-nitrobenzene |
| Conteltinib-012 | 761440-65-7 | 1-(1-(3-methoxy-4-nitrophenyl)piperidin-4-yl)-4-methylpiperazine |
| Conteltinib-013 | 761440-75-9Available | 2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline |
| Conteltinib-014 | 109-86-4 | 2-methoxyethan-1-ol |
| Conteltinib-015 | 2139336-90-4 | 4-chloro-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-7-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-amine |
| Conteltinib-016 | 761435-31-8 | 2-amino-N-isopropylbenzenesulfonamide |
| Conteltinib-017 | 2139336-91-5 | N-isopropyl-2-((2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-7-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzenesulfonamide |
OriginatorRoute 1Steps 10 · Total yield 912 mg (Vonoprazan Fumarate)
VONO-001445-27-2VONO-002655-15-2VONO-003105-56-6VONO-004881673-98-9VONO-005881674-01-7VONO-006881674-06-2VONO-007881674-58-4VONO-008881674-56-2VONO-00942899-76-3VONO-010881677-11-8VONO-011110-17-8VONO-012636-73-7API · Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-001 | 445-27-2Available | 1-(2-fluorophenyl)ethanone |
| VONO-002 | 655-15-2Available | 2-bromo-1-(2-fluorophenyl)ethanone |
| VONO-003 | 105-56-6Available | ethyl 2-cyanoacetate |
| VONO-004 | 881673-98-9Available | ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate |
| VONO-005 | 881674-01-7Available | ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate |
| VONO-006 | 881674-06-2Available | ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate |
| VONO-007 | 881674-58-4Available | (5-(2-fluorophenyl)-1H-pyrrol-3-yl)methanol |
| VONO-008 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-009 | 42899-76-3Available | pyridine-3-sulfonyl chloride hydrochloride |
| VONO-010 | 881677-11-8Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
| VONO-011 | 110-17-8Available | fumaric acid |
| VONO-012 | 636-73-7Available | pyridine-3-sulfonic acid |
OptimisedRoute 2Steps 5 · Total yield 20.7 g (Vonoprazan Fumarate)
VONO-008881674-56-2VONO-0131610043-62-3VONO-0141610043-63-4VONO-01516133-25-8VONO-0161831110-76-9VONO-011110-17-8API · Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-008 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-013 | 1610043-62-3Available | 1-(5-(2-fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine |
| VONO-014 | 1610043-63-4Available | tert-butyl ((5-(2-fluorophenyl)-1H-pyrrol-3-yl)methyl)(methyl)carbamate |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-016 | 1831110-76-9Available | tert-butyl ((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)carbamate |
| VONO-011 | 110-17-8Available | fumaric acid |
OptimisedRoute 3Steps 6 · Total yield 7.57 g (Vonoprazan Fumarate)
VONO-001445-27-2VONO-002655-15-2VONO-017—VONO-018—VONO-019881674-56-2VONO-01516133-25-8VONO-010881677-11-8Vonoprazan Fumarate1260141-27-2API · Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-001 | 445-27-2Available | 1-(2-fluorophenyl)ethanone |
| VONO-002 | 655-15-2Available | 2-bromo-1-(2-fluorophenyl)ethanone |
| VONO-017 | - | 2-(2-fluorobenzoyl)malononitrile |
| VONO-018 | - | 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile |
| VONO-019 | 881674-56-2Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-010 | 881677-11-8Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
| Vonoprazan Fumarate | 1260141-27-2Available | - |
OptimisedRoute 4Steps 3 · Total yield /
VONO-0201240948-77-9VONO-01516133-25-8VONO-0211807642-39-2VONO-0221807642-41-6API · Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate
| Code | CAS No. | Intermediate |
|---|---|---|
| VONO-020 | 1240948-77-9Available | 5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile |
| VONO-015 | 16133-25-8Available | pyridine-3-sulfonyl chloride |
| VONO-021 | 1807642-39-2Available | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbonitrile |
| VONO-022 | 1807642-41-6Available | (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine |
Frequently asked questions
When does the Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate patent expire?
No public expiry year is available for Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate yet; this page updates once verified.
How many synthesis routes are recorded for Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate?
5 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate intermediates?
23 intermediate CAS of Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Dextran/Calcium Chloride/Potassium Chloride/Sodium Chloride/Sodium lactate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29