Mitapivat sulfate
Tier C — Watch / tradeMitapivat sulfate
Targets：Pyruvate kinase
Brand：Pyrukynd, Aqvesme
Indications (approved)：α-地中海贫血, Beta thalassaemia, 丙酮酸激酶缺乏症, Haemolytic anaemia
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| MITAP-001 | 94-09-7 | ethyl 4-aminobenzoate |
| MITAP-002 | 18704-37-5 | quinoline-8-sulfonyl chloride |
| MITAP-003 | 208175-71-7 | ethyl 4-(quinoline-8-sulfonamido)benzoate |
| MITAP-004 | 116834-64-1 | 4-(quinoline-8-sulfonamido)benzoic acid |
| MITAP-005 | 57260-71-6Available | tert-butyl piperazine-1-carboxylate |
| MITAP-006 | 1260081-86-4 | tert-butyl 4-(4-(quinoline-8-sulfonamido)benzoyl)piperazine-1-carboxylate |
| MITAP-007 | 1260081-87-5 | N-(4-(piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide |
| MITAP-008 | 1489-69-6 | cyclopropanecarbaldehyde |
| Mitapivat | - | - |
Frequently asked questions
What are the approved indications of Mitapivat sulfate?
Approved indications include: α-地中海贫血, Beta thalassaemia, 丙酮酸激酶缺乏症, Haemolytic anaemia.
When does the Mitapivat sulfate patent expire?
No public expiry year is available for Mitapivat sulfate yet; this page updates once verified.
How many synthesis routes are recorded for Mitapivat sulfate?
1 synthesis routes are recorded; the shortest is 5 steps with 0.035 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Mitapivat sulfate intermediates?
1 intermediate CAS of Mitapivat sulfate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Mitapivat sulfate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29