Nitisinone
Tier C — Watch / tradeNitisinone
Targets：4HPPD
Brand：HARLIKU, Orfadin, Nityr
Indications (approved)：黑尿症, 酪氨酸血症
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| NITI-001 | 504-02-9 | cyclohexane-1,3-dione |
| NITI-002 | 81108-81-8 | 2-nitro-4-(trifluoromethyl)benzoyl chloride |
Frequently asked questions
What are the approved indications of Nitisinone?
Approved indications include: 黑尿症, 酪氨酸血症.
When does the Nitisinone patent expire?
No public expiry year is available for Nitisinone yet; this page updates once verified.
How many synthesis routes are recorded for Nitisinone?
1 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Nitisinone intermediates?
All intermediates in Nitisinone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Nitisinone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29