Apabetalone
Tier C — Watch / tradeApabetalone
Targets：BRD4, BET
Indications (approved)：新冠后遗症, End-stage renal disease, Pulmonary arterial hypertension, Fabry disease, COVID-19, Dyslipidaemia, Type 2 diabetes, Coronary artery lesion
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| APAB-004 | 63920-73-0 | 2-amino-4,6-dimethoxybenzamide |
| APAB-005 | 1044872-73-2 | 4-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-3,5-dimethylbenzaldehyde |
| Code | CAS No. | Intermediate |
|---|---|---|
| APAB-001 | 2233-18-3 | 4-hydroxy-3,5-dimethylbenzaldehyde |
| APAB-002 | 96-49-1 | 1,3-dioxolan-2-one |
| APAB-003 | 1039948-89-4 | 4-(2-hydroxyethoxy)-3,5-dimethylbenzaldehyde |
| APAB-004 | 63920-73-0 | 2-amino-4,6-dimethoxybenzamide |
Frequently asked questions
What are the approved indications of Apabetalone?
Approved indications include: 新冠后遗症, End-stage renal disease, Pulmonary arterial hypertension, Fabry disease, COVID-19, Dyslipidaemia, Type 2 diabetes, Coronary artery lesion.
When does the Apabetalone patent expire?
No public expiry year is available for Apabetalone yet; this page updates once verified.
How many synthesis routes are recorded for Apabetalone?
2 synthesis routes are recorded; the shortest is 1 steps with 444 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Apabetalone intermediates?
All intermediates in Apabetalone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Apabetalone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-11