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Cebranopadol hemicitrate

Tier C — Watch / trade

Cebranopadol hemicitrate

Grunenthal Gmbh
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:OOR, MOR1

Indications (approved):Pain, 急性疼痛, 神经痛, Low back pain, Substance-related disorder, Chronic pain, Neoplasm, Heart disease

Regional status

US
Phase III
2024-07-18
EU
Phase I
2022-07-29
China
-
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 6 · Total yield 640mg
CEBR-0014746-97-8CEBR-0021071066-97-1CEBR-00365619-82-1CEBR-00465619-20-7CEBR-005101349-12-6CEBR-006—CEBR-007823-85-8CEBR-0081191-99-7API · Cebranopadol hemicitrate
CodeCAS No.Intermediate
CEBR-0014746-97-81,4-dioxaspiro[4.5]decan-8-one
CEBR-0021071066-97-1N-methyl-1,4-dioxaspiro[4.5]decan-8-imine
CEBR-00365619-82-14-(methylamino)-4-phenylcyclohexan-1-one
CEBR-00465619-20-74-(dimethylamino)-4-phenylcyclohexan-1-one
CEBR-005101349-12-62-(5-fluoro-1H-indol-3-yl)ethan-1-ol
CEBR-006-(1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine
CEBR-007823-85-8(4-fluorophenyl)hydrazine hydrochloride
CEBR-0081191-99-72,3-dihydrofuran

Frequently asked questions

What are the approved indications of Cebranopadol hemicitrate?

Approved indications include: Pain, 急性疼痛, 神经痛, Low back pain, Substance-related disorder, Chronic pain, Neoplasm, Heart disease.

When does the Cebranopadol hemicitrate patent expire?

No public expiry year is available for Cebranopadol hemicitrate yet; this page updates once verified.

How many synthesis routes are recorded for Cebranopadol hemicitrate?

1 synthesis routes are recorded; the shortest is 6 steps with 640mg total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Cebranopadol hemicitrate intermediates?

All intermediates in Cebranopadol hemicitrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Cebranopadol hemicitrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-13