Oxcarbazepine

Tier C — Watch / trade

Oxcarbazepine

Novartis

Originator

2000

First approval

Expiry (public)

$0.12B ▲

Peak sales

Small molecule

Type

Targets：SCNA

Brand：Epilexter, Epliga, Trileptal, Oxtellar XR

Indications (approved)：Seizure

Regional status

Approved

2000-01-14

Discontinued

2002-06-01

China

Approved

2003-06-20

Japan

No progress

2009-09-01

Synthetic routes & intermediates6 routes

Originator routes × 0Optimised (non-patent) × 6Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 3 · Total yield 49 g

OXCA-0014698-11-7OXCA-00228721-08-6OXCA-00328721-09-7Oxcarbazepine28721-07-5API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-001	4698-11-7	10-methoxy-5H-dibenzo[b,f]azepine
OXCA-002	28721-08-6	10-methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride
OXCA-003	28721-09-7	10-methoxy-5H-dibenzo[b,f]azepine-5-carboxamide
Oxcarbazepine	28721-07-5 Available	10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

OptimisedRoute 2Steps 2 · Total yield 23 g

OXCA-00442787-75-7OXCA-00578880-63-4API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-004	42787-75-7	5H-dibenzo[b,f]azepine-5-carbonitrile
OXCA-005	78880-63-4	10-nitro-5H-dibenzo[b,f]azepine-5-carbonitrile

OptimisedRoute 3Steps 4 · Total yield /

OXCA-00695-53-4OXCA-00776041-86-6OXCA-008332081-60-4OXCA-00910464-31-0OXCA-01021737-58-6API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-006	95-53-4	o-toluidine
OXCA-007	76041-86-6	2-bromo-N,N-diethylbenzamide
OXCA-008	332081-60-4	2-(benzyl(o-tolyl)amino)-N,N-diethylbenzamide
OXCA-009	10464-31-0	5-benzyl-5H-dibenzo[b,f]azepin-10(11H)-one
OXCA-010	21737-58-6	5H-dibenzo[b,f]azepin-10(11H)-one

OptimisedRoute 4Steps 1 · Total yield 15.5g

OXCA-0014698-11-7API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-001	4698-11-7	10-methoxy-5H-dibenzo[b,f]azepine

OptimisedRoute 5Steps 5 · Total yield /

OXCA-0014698-11-7OXCA-00328721-09-7OXCA-0113335-98-6OXCA-012353497-35-5OXCA-013353497-37-7API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-001	4698-11-7	10-methoxy-5H-dibenzo[b,f]azepine
OXCA-003	28721-09-7	10-methoxy-5H-dibenzo[b,f]azepine-5-carboxamide
OXCA-011	3335-98-6	1-phenylindolin-2-one
OXCA-012	353497-35-5	2-(2-((methoxycarbonyl)(phenyl)amino)phenyl)acetic acid
OXCA-013	353497-37-7	methyl 10-methoxy-5H-dibenzo[b,f]azepine-5-carboxylate

OptimisedRoute 6Steps 4 · Total yield 50.1 g

OXCA-0014698-11-7OXCA-0113335-98-6OXCA-012353497-35-5OXCA-013353497-37-7API · Oxcarbazepine

Code	CAS No.	Intermediate
OXCA-001	4698-11-7	10-methoxy-5H-dibenzo[b,f]azepine
OXCA-011	3335-98-6	1-phenylindolin-2-one
OXCA-012	353497-35-5	2-(2-((methoxycarbonyl)(phenyl)amino)phenyl)acetic acid
OXCA-013	353497-37-7	methyl 10-methoxy-5H-dibenzo[b,f]azepine-5-carboxylate

Frequently asked questions

What are the approved indications of Oxcarbazepine?

Approved indications include: Seizure.

When does the Oxcarbazepine patent expire?

No public expiry year is available for Oxcarbazepine yet; this page updates once verified.

How many synthesis routes are recorded for Oxcarbazepine?

6 synthesis routes are recorded; the shortest is 1 steps with 15.5g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Oxcarbazepine intermediates?

1 intermediate CAS of Oxcarbazepine are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Oxcarbazepine intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29