Rifaquizinone
Tier C — Watch / tradeRifaquizinone
Targets：RNAP, Bacterial DNA gyrase, Topoisomerase IV
Indications (approved)：假体相关感染, 糖尿病足溃疡, Infectious skin disease, Skin and skin structure infection, Bacterial skin disease, Helicobacter pylori infection, 高氨血症, 肝性脑病
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| TNP-2092-001 | 101385-90-4 | (S)-1-benzylpyrrolidin-3-ol |
| TNP-2092-002 | 118354-71-5 | (S)-1-benzylpyrrolidin-3-yl methanesulfonate |
| TNP-2092-003 | 157528-56-8 | (R)-1-benzylpyrrolidine-3-carbonitrile |
| TNP-2092-004 | 851388-54-0 | (R)-1-(1-benzylpyrrolidin-3-yl)cyclopropan-1-amine |
| TNP-2092-005 | 79099-07-3Available | tert-butyl 4-oxopiperidine-1-carboxylate |
| TNP-2092-006 | 922718-05-6 | tert-butyl (R)-4-((1-(1-benzylpyrrolidin-3-yl)cyclopropyl)(methyl)amino)piperidine-1-carboxylate |
| TNP-2092-007 | 922718-06-7 | tert-butyl (R)-4-(methyl(1-(pyrrolidin-3-yl)cyclopropyl)amino)piperidine-1-carboxylate |
| TNP-2092-008 | 220593-79-3 | 8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid |
| TNP-2092-009 | 922718-07-8 | ethyl (R)-8-(3-(1-((1-(tert-butoxycarbonyl)piperidin-4-yl)(methyl)amino)cyclopropyl)pyrrolidin-1-yl)-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylate |
| TNP-2092-010 | 922718-08-9 | (R)-8-(3-(1-((1-(tert-butoxycarbonyl)piperidin-4-yl)(methyl)amino)cyclopropyl)pyrrolidin-1-yl)-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid |
| TNP-2092-011 | 922718-09-0 | (R)-1-cyclopropyl-7-fluoro-9-methyl-8-(3-(1-(methyl(piperidin-4-yl)amino)cyclopropyl)pyrrolidin-1-yl)-4-oxo-4H-quinolizine-3-carboxylic acid |
| TNP-2092-012 | 13292-22-3 | - |
Frequently asked questions
What are the approved indications of Rifaquizinone?
Approved indications include: 假体相关感染, 糖尿病足溃疡, Infectious skin disease, Skin and skin structure infection, Bacterial skin disease, Helicobacter pylori infection, 高氨血症, 肝性脑病.
When does the Rifaquizinone patent expire?
No public expiry year is available for Rifaquizinone yet; this page updates once verified.
How many synthesis routes are recorded for Rifaquizinone?
1 synthesis routes are recorded; the shortest is 9 steps with 8.5 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Rifaquizinone intermediates?
1 intermediate CAS of Rifaquizinone are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Rifaquizinone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-08