Diazo-oxo-L-norleucine

Tier C — Watch / trade

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：NMDAR

Indications (approved)：脑型疟疾

Regional status

China

Japan

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield /

DOLN-00171989-18-9DOLN-002160002-61-9DOLN-003145038-49-9DOLN-00457933-83-2DOLN-005—DOLN-006910891-95-1Diazo-oxo-L-norleucine157-03-9API · Diazo-oxo-L-norleucine

Code	CAS No.	Intermediate
DOLN-001	71989-18-9	(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid
DOLN-002	160002-61-9	(S)-5-tert-butyl 1-methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanedioate
DOLN-003	145038-49-9	(S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid
DOLN-004	57933-83-2	prop-1-en-2-yl carbonochloridate
DOLN-005	-	(S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic (prop-1-en-2-yl carbonic) anhydride
DOLN-006	910891-95-1	(S)-methyl 2-amino-6-diazo-5-oxohexanoate
Diazo-oxo-L-norleucine	157-03-9	-

OptimisedRoute 2Steps 3 · Total yield 210 mg (Diazo-oxo-L-norleucine)

DOLN-0077149-65-7DOLN-008208519-94-2DOLN-009208520-02-9Diazo-oxo-L-norleucine157-03-9API · Diazo-oxo-L-norleucine

Code	CAS No.	Intermediate
DOLN-007	7149-65-7	(S)-ethyl 5-oxopyrrolidine-2-carboxylate
DOLN-008	208519-94-2	(S)-1-((9H-fluoren-9-yl)methyl) 2-ethyl 5-oxopyrrolidine-1,2-dicarboxylate
DOLN-009	208520-02-9	(S)-ethyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-diazo-5-oxohexanoate
Diazo-oxo-L-norleucine	157-03-9	-

Frequently asked questions

What are the approved indications of Diazo-oxo-L-norleucine?

Approved indications include: 脑型疟疾.

When does the Diazo-oxo-L-norleucine patent expire?

No public expiry year is available for Diazo-oxo-L-norleucine yet; this page updates once verified.

How many synthesis routes are recorded for Diazo-oxo-L-norleucine?

2 synthesis routes are recorded; the shortest is 3 steps with 210 mg (Diazo-oxo-L-norleucine) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Diazo-oxo-L-norleucine intermediates?

All intermediates in Diazo-oxo-L-norleucine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Diazo-oxo-L-norleucine intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-05