Lidocaine/Prilocaine cutaneous spray

Tier C — Watch / trade

Recordati Ireland Ltd

Originator

2013

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：SCNA, VDCCs

Brand：Senstend, Fortacin

Indications (approved)：Premature ejaculation, Physiological sexual dysfunction

Regional status

Phase III

2007-10-01

Approved

2013-11-15

China

Approved

2026-06-10

Japan

Factories producing this API11

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

11 producing factories on file — sign in to view the named list (factory details are not shown to guests).

Synthetic routes & intermediates3 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 2

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 3Steps 2 · Total yield /

Lidocaine Hydrochloride-023—Lidocaine Hydrochloride-024—Lidocaine Hydrochloride-025—Lidocaine Hydrochloride-010—API · Lidocaine/Prilocaine cutaneous spray

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-023	-	N-Formyldiethylamine
Lidocaine Hydrochloride-024	-	N-Ethyl-N-[(tributylstannyl)methyl]ethanamine
Lidocaine Hydrochloride-025	-	2-Isocyanato-1,3-dimethylbenzene
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide

ProcessRoute 1Steps 8 · Total yield 93.4kg(Lidocaine Hydrochloride (API))

Lidocaine Hydrochloride-001—Lidocaine Hydrochloride-002—Lidocaine Hydrochloride-003—Lidocaine Hydrochloride-004—Lidocaine Hydrochloride-005—Lidocaine Hydrochloride-006—Lidocaine Hydrochloride-007—Lidocaine Hydrochloride-008—Lidocaine Hydrochloride-009—Lidocaine Hydrochloride-010—Lidocaine Hydrochloride-011—Lidocaine Hydrochloride-01259858-41-2Lidocaine Hydrochloride-013—Lidocaine Hydrochloride-014—Lidocaine Hydrochloride-015—Lidocaine Hydrochloride-016—Lidocaine Hydrochloride-017—API · Lidocaine/Prilocaine cutaneous spray

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-001	-	1,3-Dimethyl-2-nitrobenzene
Lidocaine Hydrochloride-002	-	2-Amino-1,3-dimethylbenzene
Lidocaine Hydrochloride-003	-	2-Bromanylethanoic acid
Lidocaine Hydrochloride-004	-	2-Chloroacetic acid
Lidocaine Hydrochloride-005	-	2-Chloranylethanoyl chloride
Lidocaine Hydrochloride-006	-	2-Chloroacetic acid methyl ester
Lidocaine Hydrochloride-007	-	2-Bromo-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-008	-	1-Chloroacetylamino-2,6-dimethylbenzene
Lidocaine Hydrochloride-009	-	N-Ethylethanamine
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-011	-	2-(Diethylamino)acetic acid
Lidocaine Hydrochloride-012	59858-41-2	2-(Diethylamino)acetyl chloride
Lidocaine Hydrochloride-013	-	Methyl 2-(diethylamino)acetate
Lidocaine Hydrochloride-014	-	3-(2-Methoxyphenyl)-1H-pyrazole
Lidocaine Hydrochloride-015	-	2-(Chloromethyl)pyridine hydrochloride
Lidocaine Hydrochloride-016	-	-
Lidocaine Hydrochloride-017	-	Dichloridomanganese 2-[[3-(2-methoxyphenyl)-1H-pyrazol-1-yl]methyl]pyridine

ProcessRoute 2Steps 2 · Total yield 441.0666g(Lidocaine (Free))

Lidocaine Hydrochloride-002—Lidocaine Hydrochloride-01844978-98-5Lidocaine Hydrochloride-01927794-54-3Lidocaine Hydrochloride-020134756-56-2Lidocaine Hydrochloride-0211546682-40-9Lidocaine Hydrochloride-010—Lidocaine Hydrochloride-009—Lidocaine Hydrochloride-022—API · Lidocaine/Prilocaine cutaneous spray

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-002	-	2-Amino-1,3-dimethylbenzene
Lidocaine Hydrochloride-018	44978-98-5	N2,N2-Diethyl-N,N-dimethylglycinamide
Lidocaine Hydrochloride-019	27794-54-3	N,N,N2,N2-Tetraethylglycinamide
Lidocaine Hydrochloride-020	134756-56-2	N2,N2-Diethyl-N,N-dipropan-2-ylglycinamide
Lidocaine Hydrochloride-021	1546682-40-9	N2,N2-Diethyl-N,N-dipropylglycinamide
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-009	-	N-Ethylethanamine
Lidocaine Hydrochloride-022	-	N-(2,6-Dimethylphenyl)-2-hydroxyacetamide

Frequently asked questions

What are the approved indications of Lidocaine/Prilocaine cutaneous spray?

Approved indications include: Premature ejaculation, Physiological sexual dysfunction.

When does the Lidocaine/Prilocaine cutaneous spray patent expire?

No public expiry year is available for Lidocaine/Prilocaine cutaneous spray yet; this page updates once verified.

How many synthesis routes are recorded for Lidocaine/Prilocaine cutaneous spray?

3 synthesis routes are recorded; the shortest is 2 steps with 441.0666g(Lidocaine (Free)) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Lidocaine/Prilocaine cutaneous spray intermediates?

All intermediates in Lidocaine/Prilocaine cutaneous spray routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Lidocaine/Prilocaine cutaneous spray intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29