Mefuparib Hydrochloride
Tier C — Watch / tradeMefuparib Hydrochloride
Targets：PARP
Indications (approved)：Bile duct cancer, Breast cancer, Pancreatic cancer, Solid tumour, Castration-resistant prostate cancer, Bladder cancer, Glioma, Urinary tract neoplasm
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Mefuparib-001 | 345-16-4 | 5-fluoro-2-hydroxybenzoic acid |
| Mefuparib-002 | 391-92-4 | methyl 5-fluoro-2-hydroxybenzoate |
| Mefuparib-003 | 4068-69-3 | methyl 5-fluoro-2-hydroxy-3-iodobenzoate |
| Mefuparib-004 | 1449746-06-8 | 1-(4-ethynylphenyl)-N-methylmethanamine |
| Mefuparib-005 | 1449746-07-9 | methyl 5-fluoro-2-(4-((methylamino)methyl)phenyl)benzofuran-7-carboxylate |
| Mefuparib-006 | 63697-96-1 | 4-ethynylbenzaldehyde |
| Mefuparib | 1392502-82-7 | 7-Benzofurancarboxamide, 5-fluoro-2-[4-[(methylamino)methyl]phenyl]- |
Frequently asked questions
What are the approved indications of Mefuparib Hydrochloride?
Approved indications include: Bile duct cancer, Breast cancer, Pancreatic cancer, Solid tumour, Castration-resistant prostate cancer, Bladder cancer, Glioma, Urinary tract neoplasm.
When does the Mefuparib Hydrochloride patent expire?
No public expiry year is available for Mefuparib Hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Mefuparib Hydrochloride?
1 synthesis routes are recorded; the shortest is 5 steps with 2.7 g (Mefuparib) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Mefuparib Hydrochloride intermediates?
All intermediates in Mefuparib Hydrochloride routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Mefuparib Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-21