Bupivacaine

Tier C — Watch / trade

Bupivacaine

Cellix Bio Pvt Ltd

Originator

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：Sodium channels

Brand：BupiZenge

Indications (approved)：Subacromial impingement syndrome, Postoperative pain

Regional status

Approved

Phase III

2026-07-07

China

Japan

Factories producing this API2

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

2 producing factories on file — sign in to view the named list (factory details are not shown to guests).

Synthetic routes & intermediates3 routes

Originator routes × 0Optimised (non-patent) × 3Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 3 · Total yield /

(I)91311-1-a535-75-1(II)91311-1-a71170-88-2(III)91311-1-a87-62-7(IV)91311-1-a—(V)91311-1-a15883-20-2(VI)91311-1-a109-65-9API · Bupivacaine

Code	CAS No.	Intermediate
(I)91311-1-a	535-75-1	(+/-)-Piperidine-2-carboxylic acid
(II)91311-1-a	71170-88-2	1-[(Benzyloxy)carbonyl]piperidine-2-carboxylic acid
(III)91311-1-a	87-62-7 Available	2-Amino-1,3-dimethylbenzene
(IV)91311-1-a	-	Phenyl 2-[(2,6-dimethylphenyl)carbamoyl]piperidine-1-carboxylate
(V)91311-1-a	15883-20-2 Available	(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
(VI)91311-1-a	109-65-9	1-Bromobutane

OptimisedRoute 2Steps 4 · Total yield /

(I)91311-2-a535-75-1(II)91311-2-a15862-86-9(III)91311-2-a36293-02-4(IV)91311-2-a87-62-7(V)91311-2-a15883-20-2(VI)91311-2-a109-65-9API · Bupivacaine

Code	CAS No.	Intermediate
(I)91311-2-a	535-75-1	(+/-)-Piperidine-2-carboxylic acid
(II)91311-2-a	15862-86-9	DL-Pipecolic acid hydrochloride
(III)91311-2-a	36293-02-4	Piperidine-2-carbonyl chloride hydrogen chloride
(IV)91311-2-a	87-62-7 Available	2-Amino-1,3-dimethylbenzene
(V)91311-2-a	15883-20-2 Available	(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
(VI)91311-2-a	109-65-9	1-Bromobutane

OptimisedRoute 3Steps 1 · Total yield /

(I)91311-3-a87-62-7(II)91311-3-a—(III)91311-3-a—API · Bupivacaine

Code	CAS No.	Intermediate
(I)91311-3-a	87-62-7 Available	2-Amino-1,3-dimethylbenzene
(II)91311-3-a	-	1-Butylpiperidine-2-carbaldehyde
(III)91311-3-a	-	1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

Frequently asked questions

What are the approved indications of Bupivacaine?

Approved indications include: Subacromial impingement syndrome, Postoperative pain.

When does the Bupivacaine patent expire?

No public expiry year is available for Bupivacaine yet; this page updates once verified.

How many synthesis routes are recorded for Bupivacaine?

3 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Bupivacaine intermediates?

2 intermediate CAS of Bupivacaine are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Bupivacaine intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29