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Misoprostol

Tier C — Watch / trade

Misoprostol

Pfizer Inc.
Originator
1984
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PTGER2

Brand:Isprelor, Cytotec, Mysodelle, Misodel, Angusta, Misopess, Misotac, Vagiprost, GyMiso

Indications (approved):Termination of pregnancy, Duodenal ulcer, Gastric ulcer, Gastric cancer, Peptic ulcer

Regional status

US
Approved
1988-12-27
EU
Approved
1984-06-28
China
Approved
1996-01-01
Japan
Approved
1993-01-19

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield /
MISO-00122128-43-4MISO-00266792-28-7MISO-00362555-05-9MISO-00419093-51-7MISO-005—MISO-006—Misoprostol59122-46-2API · Misoprostol
CodeCAS No.Intermediate
MISO-00122128-43-44-methyloct-1-yn-4-ol
MISO-00266792-28-7trimethyl((4-methyloct-1-yn-4-yl)oxy)silane
MISO-00362555-05-9(E)-((1-iodo-4-methyloct-1-en-4-yl)oxy)trimethylsilane
MISO-00419093-51-7pent-1-yn-1-ylcopper
MISO-005-methyl 7-((1R,4S)-2-oxo-4-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
MISO-006-methyl 7-((1R,4S)-2-oxo-4-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
Misoprostol59122-46-2methyl 7-((1R,2R,3R)-2-((E)-4-methyl-4-((trimethylsilyl)oxy)oct-1-en-1-yl)-5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate

Frequently asked questions

What are the approved indications of Misoprostol?

Approved indications include: Termination of pregnancy, Duodenal ulcer, Gastric ulcer, Gastric cancer, Peptic ulcer.

When does the Misoprostol patent expire?

No public expiry year is available for Misoprostol yet; this page updates once verified.

How many synthesis routes are recorded for Misoprostol?

1 synthesis routes are recorded; the shortest is 5 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Misoprostol intermediates?

All intermediates in Misoprostol routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Misoprostol intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29