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Vorasidenib

Tier C — Watch / trade

Vorasidenib

Agios Pharmaceuticals Inc
Originator
2024
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:IDH1, IDH2

Brand:VORANIGO

Indications (approved):神经胶质瘤, 少突神经胶质瘤, 星形细胞瘤, Glioma

Regional status

US
Approved
2024-08-06
EU
Approved
2025-09-17
China
Filed / under review
2026-05-08
Japan
Approved
2025-09-22

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield /
VORASI-0016636-55-1VORASI-002108-19-0VORASI-0031446507-37-4VORASI-0041446507-39-6VORASI-005177469-12-4Vorasidenib1644545-52-7API · Vorasidenib
CodeCAS No.Intermediate
VORASI-0016636-55-1methyl 6-chloropicolinate
VORASI-002108-19-0-
VORASI-0031446507-37-46-(6-chloropyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione
VORASI-0041446507-39-62,4-dichloro-6-(6-chloropyridin-2-yl)-1,3,5-triazine
VORASI-005177469-12-4(R)-1,1,1-trifluoropropan-2-amine hydrochloride
Vorasidenib1644545-52-76-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine

Frequently asked questions

What are the approved indications of Vorasidenib?

Approved indications include: 神经胶质瘤, 少突神经胶质瘤, 星形细胞瘤, Glioma.

When does the Vorasidenib patent expire?

No public expiry year is available for Vorasidenib yet; this page updates once verified.

How many synthesis routes are recorded for Vorasidenib?

1 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Vorasidenib intermediates?

All intermediates in Vorasidenib routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Vorasidenib intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29