Floxacillin sodium
Tier C — Watch / tradeFloxacillin sodium
Targets：PBPs
Brand：Floxapen, Staphylex
Indications (approved)：Bacterial infection
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| (I)70425-1-a | 387-45-1 | 2-Chloro-6-fluorobenzaldehyde |
| (II)70425-1-a | 443-33-4 | 2-Chloro-6-fluorobenzaldehyde oxime |
| (III)70425-1-a | 51088-25-6 | 2-Chloro-6-fluoro-N-hydroxybenzenecarboximidoyl chloride |
| (IV)70425-1-a | 105-45-3Available | 1-Methoxybutane-1,3-dione |
| (V)70425-1-a | 4415-09-2 | Methyl 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate |
| (VI)70425-1-a | 3919-74-2 | 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid |
| (VII)70425-1-a | 69399-79-7 | 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride |
| (VIII)70425-1-a | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| (I)70425-2-a | 3919-74-2 | 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid |
| (IIa)70425-2-a | 1678555-65-1 | 3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic 2,2-dimethylpropanoic anhydride |
| (IIb)70425-2-a | 2354195-23-4 | S-1,3-Benzothiazol-2-yl 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbothioate |
| (IIIa)70425-2-a | 19460-36-7 | (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N-diethylethanamine |
| (IIIb)70425-2-a | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| (IVa)70425-2-a | 1678555-66-2 | (2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N-diethylethanamine |
| (IVb)70425-2-a | 5250-39-5 | (2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| (I)70425-3-a | 551-16-6Available | (+)-6-Aminopenicillanic acid |
| (IIa)70425-3-a | - | Sodium (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| (IIb)70425-3-a | - | Potassium (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| (III)70425-3-a | 69399-79-7 | 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride |
| (IV)70425-3-a | 5250-39-5 | (2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
Frequently asked questions
What are the approved indications of Floxacillin sodium?
Approved indications include: Bacterial infection.
When does the Floxacillin sodium patent expire?
No public expiry year is available for Floxacillin sodium yet; this page updates once verified.
How many synthesis routes are recorded for Floxacillin sodium?
3 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Floxacillin sodium intermediates?
2 intermediate CAS of Floxacillin sodium are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Floxacillin sodium intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29