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Mifepristone/Misoprostol

Tier C — Watch / trade

Mifepristone/Misoprostol

Sun Pharmaceutical Industries Ltd.
Originator
2012
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PTGER2, PR

Brand:Mifegymiso, Medabon, MS-2 Step, MEFEEGO

Indications (approved):Termination of pregnancy

Regional status

US
-
EU
Approved
2012-01-01
China
-
Japan
Approved
2023-04-28

Factories producing this API11

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates3 routes

Originator routes × 2Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 4 · Total yield 0.93 g
MIFE-0015571-36-8MIFE-00274-99-7MIFE-00384371-69-7MIFE-004684-16-2MIFE-00584371-57-3MIFE-0067353-91-5MIFE-007—API · Mifepristone/Misoprostol
CodeCAS No.Intermediate
MIFE-0015571-36-8(8S,13S,14S)-13-methyl-1,4,6,7,8,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17(2H)-one
MIFE-00274-99-7prop-1-yne
MIFE-00384371-69-7(8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol
MIFE-004684-16-21,1,1,3,3,3-hexafluoropropan-2-one
MIFE-00584371-57-3(5'R,8'S,10'R,13'S,14'S,17'S)-13'-methyl-17'-(prop-1-yn-1-yl)-1',2',7',8',12',13',14',15',16',17'-decahydro-4'H,6'H-spiro[[1,3]dioxolane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-ol
MIFE-0067353-91-5(4-(dimethylamino)phenyl)magnesium bromide
MIFE-007-(8S,11R,13S,14S,17S)-11-(4-(dimethylamino)phenyl)-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol
OriginatorRoute 1Steps 5 · Total yield /
MISO-00122128-43-4MISO-00266792-28-7MISO-00362555-05-9MISO-00419093-51-7MISO-005—MISO-006—Misoprostol59122-46-2API · Mifepristone/Misoprostol
CodeCAS No.Intermediate
MISO-00122128-43-44-methyloct-1-yn-4-ol
MISO-00266792-28-7trimethyl((4-methyloct-1-yn-4-yl)oxy)silane
MISO-00362555-05-9(E)-((1-iodo-4-methyloct-1-en-4-yl)oxy)trimethylsilane
MISO-00419093-51-7pent-1-yn-1-ylcopper
MISO-005-methyl 7-((1R,4S)-2-oxo-4-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
MISO-006-methyl 7-((1R,4S)-2-oxo-4-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
Misoprostol59122-46-2methyl 7-((1R,2R,3R)-2-((E)-4-methyl-4-((trimethylsilyl)oxy)oct-1-en-1-yl)-5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
OptimisedRoute 2Steps 2 · Total yield 22.50 g
MIFE-008510-64-5MIFE-0091562787-62-5MIFE-0105173-46-6API · Mifepristone/Misoprostol
CodeCAS No.Intermediate
MIFE-008510-64-5(8R,13S,14S)-10-(hydroxymethyl)-13-methyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione
MIFE-0091562787-62-5(8S,13S,14S)-13-methyl-3,17-dioxo-1,2,3,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-10H-cyclopenta[a]phenanthren-10-yl acetate
MIFE-0105173-46-6(8S,13S,14S)-13-methyl-1,6,7,8,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione

Frequently asked questions

What are the approved indications of Mifepristone/Misoprostol?

Approved indications include: Termination of pregnancy.

When does the Mifepristone/Misoprostol patent expire?

No public expiry year is available for Mifepristone/Misoprostol yet; this page updates once verified.

How many synthesis routes are recorded for Mifepristone/Misoprostol?

3 synthesis routes are recorded; the shortest is 2 steps with 22.50 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Mifepristone/Misoprostol intermediates?

All intermediates in Mifepristone/Misoprostol routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Mifepristone/Misoprostol intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29