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Rifabutin

Tier C — Watch / trade

Rifabutin

Pfizer Inc.
Originator
1992
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:RNAP

Brand:Mycobutin, Ansatipin, Ansatipine

Indications (approved):Multidrug-resistant tuberculosis, Mycobacterium avium-intracellulare complex disease

Regional status

US
Approved
1992-12-23
EU
-
China
Approved
2007-12-28
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 4 · Total yield /
RIFAB-0012353416-91-6RIFAB-0021268698-55-0RIFAB-00362041-01-4RIFAB-00472544-16-2API · Rifabutin
CodeCAS No.Intermediate
RIFAB-0012353416-91-6-
RIFAB-0021268698-55-0SMPJCQGFZSDIHE-XZEREJJPSA-N
RIFAB-00362041-01-4-
RIFAB-00472544-16-21-isobutylpiperidin-4-one

Frequently asked questions

What are the approved indications of Rifabutin?

Approved indications include: Multidrug-resistant tuberculosis, Mycobacterium avium-intracellulare complex disease.

When does the Rifabutin patent expire?

No public expiry year is available for Rifabutin yet; this page updates once verified.

How many synthesis routes are recorded for Rifabutin?

1 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Rifabutin intermediates?

All intermediates in Rifabutin routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Rifabutin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29