Selumetinib sulfate
Tier C — Watch / tradeSelumetinib sulfate · all drugs expiring in 2032 →
Targets：MEK2, MEK1
Brand：Koselugo
Indications (approved)：Plexiform neurofibroma, Neurofibromatosis type I
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| SELT-001 | 61079-72-9 | 2,3,4-trifluorobenzoic acid |
| SELT-002 | 197520-71-1 | 2,3,4-trifluoro-5-nitrobenzoic acid |
| SELT-003 | 284030-57-5 | 4-amino-2,3-difluoro-5-nitrobenzoic acid |
| SELT-004 | 284030-58-6 | methyl 4-amino-2,3-difluoro-5-nitrobenzoate |
| SELT-005 | 62-53-3Available | aniline |
| SELT-006 | 606093-58-7 | - |
| SELT-007 | 606093-59-8 | - |
| SELT-008 | 606143-93-5 | - |
| SELT-009 | 606143-46-8 | - |
| SELT-010 | 606144-02-9 | - |
| SELT-011 | 606144-04-1 | - |
| SELT-012 | 391212-29-6 | methyl 2-((2-fluoro-4-iodophenyl)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate |
| SELT-013 | 606144-05-2 | - |
Frequently asked questions
What are the approved indications of Selumetinib sulfate?
Approved indications include: Plexiform neurofibroma, Neurofibromatosis type I.
When does the Selumetinib sulfate patent expire?
Based on public sources, the Selumetinib sulfate patent expires in 2032.
How many synthesis routes are recorded for Selumetinib sulfate?
1 synthesis routes are recorded; the shortest is 11 steps with 2.11 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Selumetinib sulfate intermediates?
1 intermediate CAS of Selumetinib sulfate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Selumetinib sulfate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29