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Lamivudine/Tenofovir Disoproxil Fumarate
Tier C — Watch / tradeLamivudine/Tenofovir Disoproxil Fumarate
Mylan Nv
Originator
2018
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type
Targets：RT, HBV pol
Brand：Temixys, Cimduo
Indications (approved)：HIV infection, Chronic hepatitis B
Regional status
US
Approved
2018-02-28
EU
-
China
Approved
2019-01-15
Japan
-
Factories producing this API13
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
13 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates13 routes
Originator routes × 1Optimised (non-patent) × 12Process routes × 0
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
OriginatorRoute 1Steps 6 · Total yield 165 mg
LAMI-0013376-59-8LAMI-00264904-47-8LAMI-00353608-94-9LAMI-004138760-43-7LAMI-00571-30-7LAMI-006143957-12-4LAMI-00798-91-9LAMI-0082032-35-1LAMI-009163348-46-7API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| LAMI-001 | 3376-59-8 | 2,3-dihydroxypropyl benzoate |
| LAMI-002 | 64904-47-8 | 2-oxoethyl benzoate |
| LAMI-003 | 53608-94-9 | 2,2-diethoxyethanethiol |
| LAMI-004 | 138760-43-7 | (5-ethoxy-1,3-oxathiolan-2-yl)methyl benzoate |
| LAMI-005 | 71-30-7Available | 4-aminopyrimidin-2(1H)-one |
| LAMI-006 | 143957-12-4 | ((2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate |
| LAMI-007 | 98-91-9 | benzothioic O-acid |
| LAMI-008 | 2032-35-1 | 2-bromo-1,1-diethoxyethane |
| LAMI-009 | 163348-46-7 | S-(2,2-diethoxyethyl) benzothioate |
OptimisedRoute 2Steps 4 · Total yield /
LAMI-00264904-47-8LAMI-006143957-12-4LAMI-01030163-03-2LAMI-011143957-11-3LAMI-012143957-14-6API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| LAMI-002 | 64904-47-8 | 2-oxoethyl benzoate |
| LAMI-006 | 143957-12-4 | ((2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate |
| LAMI-010 | 30163-03-2 | (S)-2-hydroxy-3-mercaptopropanoic acid |
| LAMI-011 | 143957-11-3 | (2R,5S)-2-((benzoyloxy)methyl)-1,3-oxathiolane-5-carboxylic acid |
| LAMI-012 | 143957-14-6 | ((2R)-5-acetoxy-1,3-oxathiolan-2-yl)methyl benzoate |
OptimisedRoute 3Steps 5 · Total yield /
LAMI-00571-30-7LAMI-01389-78-1LAMI-0141152495-30-1LAMI-01526315-61-7LAMI-01640018-26-6LAMI-017—LAMI-018147126-65-6LAMI-019147027-10-9API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| LAMI-005 | 71-30-7Available | 4-aminopyrimidin-2(1H)-one |
| LAMI-013 | 89-78-1Available | (1R,2S,5R)-2-isopropyl-5-methylcyclohexan-1-ol |
| LAMI-014 | 1152495-30-1 | 2-oxoacetic acid hydrate |
| LAMI-015 | 26315-61-7 | (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-oxoacetate |
| LAMI-016 | 40018-26-6 | 1,4-dithiane-2,5-diol |
| LAMI-017 | - | (2R,5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate |
| LAMI-018 | 147126-65-6 | (2R,5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-acetoxy-1,3-oxathiolane-2-carboxylate |
| LAMI-019 | 147027-10-9 | (2R,5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate |
OptimisedRoute 4Steps 5 · Total yield /
LAMI-01389-78-1LAMI-018147126-65-6LAMI-02068-11-1LAMI-021298-12-4LAMI-022138760-34-6LAMI-023—LAMI-024200396-19-6LAMI-018-a147126-65-6API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| LAMI-013 | 89-78-1Available | (1R,2S,5R)-2-isopropyl-5-methylcyclohexan-1-ol |
| LAMI-018 | 147126-65-6 | (2R,5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-acetoxy-1,3-oxathiolane-2-carboxylate |
| LAMI-020 | 68-11-1 | 2-mercaptoacetic acid |
| LAMI-021 | 298-12-4Available | 2-oxoacetic acid |
| LAMI-022 | 138760-34-6 | 5-oxo-1,3-oxathiolane-2-carboxylic acid |
| LAMI-023 | - | (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-oxo-1,3-oxathiolane-2-carboxylate |
| LAMI-024 | 200396-19-6 | (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate |
| LAMI-018-a | 147126-65-6 | (2S,5R)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-acetoxy-1,3-oxathiolane-2-carboxylate |
OptimisedRoute 5Steps 3 · Total yield /
LAMI-00264904-47-8LAMI-012143957-14-6LAMI-01640018-26-6LAMI-02518027-23-1LAMI-0261091585-30-6API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| LAMI-002 | 64904-47-8 | 2-oxoethyl benzoate |
| LAMI-012 | 143957-14-6 | ((2R)-5-acetoxy-1,3-oxathiolan-2-yl)methyl benzoate |
| LAMI-016 | 40018-26-6 | 1,4-dithiane-2,5-diol |
| LAMI-025 | 18027-23-1 | N-(trimethylsilyl)-N-(2-((trimethylsilyl)oxy)pyrimidin-4-yl)acetamide |
| LAMI-026 | 1091585-30-6 | ((2R,5S)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate |
OptimisedRoute 1Steps 11 · Total yield 23.3g(Tenofovir disoproxil phosphate (API))
Tenofovir disoproxil phosphate-00178-95-5Tenofovir disoproxil phosphate-00219141-39-0Tenofovir disoproxil phosphate-00331618-90-3Tenofovir disoproxil phosphate-0043167-63-3Tenofovir disoproxil phosphate-005762-04-9Tenofovir disoproxil phosphate-0063084-40-0Tenofovir disoproxil phosphate-0071316848-77-7Tenofovir disoproxil phosphate-00873-24-5Tenofovir disoproxil phosphate-009180587-75-1Tenofovir disoproxil phosphate-010206184-49-8,147127-19-3,147127-20-6Tenofovir disoproxil phosphate-01135180-01-9Tenofovir disoproxil phosphate-012201341-05-1Tenofovir disoproxil phosphate-01315448-47-2Tenofovir disoproxil phosphate-01414047-28-0Tenofovir disoproxil phosphate-01516606-55-6Tenofovir disoproxil phosphate-01660456-23-7,556-52-5Tenofovir disoproxil phosphate-0174254-14-2API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-001 | 78-95-5 | Chloroacetyl chloride |
| Tenofovir disoproxil phosphate-002 | 19141-39-0 | 1-Chloro-2(R)-propanol |
| Tenofovir disoproxil phosphate-003 | 31618-90-3 | Diethyl (tosyloxy)methylphosphonate |
| Tenofovir disoproxil phosphate-004 | 3167-63-3 | Diethyl (chloromethyl)phosphonate |
| Tenofovir disoproxil phosphate-005 | 762-04-9 | Diethyl phosphonate |
| Tenofovir disoproxil phosphate-006 | 3084-40-0 | Diethyl phosphonomethanol |
| Tenofovir disoproxil phosphate-007 | 1316848-77-7 | Diethyl (2-chloro-1(R)-methylethoxy)methylphosphonate |
| Tenofovir disoproxil phosphate-008 | 73-24-5 | 6-Aminopurine |
| Tenofovir disoproxil phosphate-009 | 180587-75-1 | (R)-9-[2-(Diethylphosphonomethoxy)propyl] adenine |
| Tenofovir disoproxil phosphate-010 | 206184-49-8,147127-19-3,147127-20-6 | (R)-9-(2-Phosphonomethoxypropyl)adenine |
| Tenofovir disoproxil phosphate-011 | 35180-01-9 | Chloromethyl isopropyl carbonate |
| Tenofovir disoproxil phosphate-012 | 201341-05-1 | Bis[[(isopropoxycarbonyl)oxy]methyl] ([[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonate |
| Tenofovir disoproxil phosphate-013 | 15448-47-2 | 2(R)-Methyloxirane |
| Tenofovir disoproxil phosphate-014 | 14047-28-0 | (R)-(+)-9-(2-Hydroxypropyl)adenine |
| Tenofovir disoproxil phosphate-015 | 16606-55-6 | (R)-Propylene carbonate |
| Tenofovir disoproxil phosphate-016 | 60456-23-7,556-52-5 | (S)-Glycidol |
| Tenofovir disoproxil phosphate-017 | 4254-14-2 | (R)-1,2-Propanediol |
OptimisedRoute 2Steps 4 · Total yield 1.7g(Tenofovir disoproxil phosphate-014)
Tenofovir disoproxil phosphate-01414047-28-0Tenofovir disoproxil phosphate-01516606-55-6Tenofovir disoproxil phosphate-0184316-94-3Tenofovir disoproxil phosphate-0191492978-64-9Tenofovir disoproxil phosphate-0204316-93-2Tenofovir disoproxil phosphate-0212799-16-8Tenofovir disoproxil phosphate-022180587-74-0API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-014 | 14047-28-0 | (R)-(+)-9-(2-Hydroxypropyl)adenine |
| Tenofovir disoproxil phosphate-015 | 16606-55-6 | (R)-Propylene carbonate |
| Tenofovir disoproxil phosphate-018 | 4316-94-3 | 6-Chloro-5-nitropyrimidin-4-amine |
| Tenofovir disoproxil phosphate-019 | 1492978-64-9 | (2R)-1-[(6-Chloro-5-nitropyrimidin-4-yl)amino]propan-2-ol |
| Tenofovir disoproxil phosphate-020 | 4316-93-2 | 4,6-Dichloro-5-nitropyrimidine |
| Tenofovir disoproxil phosphate-021 | 2799-16-8 | (2R)-1-Aminopropan-2-ol |
| Tenofovir disoproxil phosphate-022 | 180587-74-0 | (2R)-1-(6-Chloro-9H-purin-9-yl)propan-2-ol |
OptimisedRoute 3Steps 8 · Total yield 21.8g(Tenofovir disoproxil phosphate-009)
Tenofovir disoproxil phosphate-005762-04-9Tenofovir disoproxil phosphate-009180587-75-1Tenofovir disoproxil phosphate-01414047-28-0Tenofovir disoproxil phosphate-022180587-74-0Tenofovir disoproxil phosphate-02387-42-3Tenofovir disoproxil phosphate-024598-31-2Tenofovir disoproxil phosphate-025100682-42-6Tenofovir disoproxil phosphate-026106938-62-9Tenofovir disoproxil phosphate-0271493808-01-7Tenofovir disoproxil phosphate-028105970-02-3API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-005 | 762-04-9 | Diethyl phosphonate |
| Tenofovir disoproxil phosphate-009 | 180587-75-1 | (R)-9-[2-(Diethylphosphonomethoxy)propyl] adenine |
| Tenofovir disoproxil phosphate-014 | 14047-28-0 | (R)-(+)-9-(2-Hydroxypropyl)adenine |
| Tenofovir disoproxil phosphate-022 | 180587-74-0 | (2R)-1-(6-Chloro-9H-purin-9-yl)propan-2-ol |
| Tenofovir disoproxil phosphate-023 | 87-42-3 | 6-Chloro-9H-purine |
| Tenofovir disoproxil phosphate-024 | 598-31-2 | 1-Bromopropan-2-one |
| Tenofovir disoproxil phosphate-025 | 100682-42-6 | 1-(6-Chloro-9H-purin-9-yl)acetone |
| Tenofovir disoproxil phosphate-026 | 106938-62-9 | Diethoxyphosphoryl)methyl triflate |
| Tenofovir disoproxil phosphate-027 | 1493808-01-7 | Diethyl [2-(6-chloropurin-9-yl)-1(R)-methylethyloxy]methylphosphonate |
| Tenofovir disoproxil phosphate-028 | 105970-02-3 | 1-(6-Amino-9H-purin-9-yl)acetone |
OptimisedRoute 4Steps 3 · Total yield 21.8g(Tenofovir disoproxil phosphate-009)
Tenofovir disoproxil phosphate-005762-04-9Tenofovir disoproxil phosphate-0063084-40-0Tenofovir disoproxil phosphate-009180587-75-1Tenofovir disoproxil phosphate-01414047-28-0Tenofovir disoproxil phosphate-029114108-84-8Tenofovir disoproxil phosphate-030145978-18-3Tenofovir disoproxil phosphate-031145978-32-1API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-005 | 762-04-9 | Diethyl phosphonate |
| Tenofovir disoproxil phosphate-006 | 3084-40-0 | Diethyl phosphonomethanol |
| Tenofovir disoproxil phosphate-009 | 180587-75-1 | (R)-9-[2-(Diethylphosphonomethoxy)propyl] adenine |
| Tenofovir disoproxil phosphate-014 | 14047-28-0 | (R)-(+)-9-(2-Hydroxypropyl)adenine |
| Tenofovir disoproxil phosphate-029 | 114108-84-8 | (Diethoxyphosphoryl)methyl methanesulfonate |
| Tenofovir disoproxil phosphate-030 | 145978-18-3 | (Diethoxyphosphoryl)methyl 4-fluorobenzene-1-sulfonate |
| Tenofovir disoproxil phosphate-031 | 145978-32-1 | (Diethoxyphosphoryl)methyl 4-(trifluoromethyl)benzene-1-sulfonate |
OptimisedRoute 5Steps 8 · Total yield 1.97g(Tenofovir disoproxil phosphate-013)
Tenofovir disoproxil phosphate-01315448-47-2Tenofovir disoproxil phosphate-0174254-14-2Tenofovir disoproxil phosphate-03279-33-4Tenofovir disoproxil phosphate-03327871-49-4Tenofovir disoproxil phosphate-03463696-98-0Tenofovir disoproxil phosphate-03524590-49-6Tenofovir disoproxil phosphate-03610326-41-7Tenofovir disoproxil phosphate-03717392-83-5Tenofovir disoproxil phosphate-038103775-61-7API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-013 | 15448-47-2 | 2(R)-Methyloxirane |
| Tenofovir disoproxil phosphate-017 | 4254-14-2 | (R)-1,2-Propanediol |
| Tenofovir disoproxil phosphate-032 | 79-33-4 | 2(S)-Hydroxypropionic acid |
| Tenofovir disoproxil phosphate-033 | 27871-49-4 | Methyl (2S)-2-hydroxypropanoate |
| Tenofovir disoproxil phosphate-034 | 63696-98-0 | Methyl (2S)-2-[(methanesulfonyl)oxy]propanoate |
| Tenofovir disoproxil phosphate-035 | 24590-49-6 | (2S)-1-Hydroxypropan-2-yl methanesulfonate |
| Tenofovir disoproxil phosphate-036 | 10326-41-7 | (2R)-2-Hydroxypropanoic acid |
| Tenofovir disoproxil phosphate-037 | 17392-83-5Available | D-Lactic acid methyl ester |
| Tenofovir disoproxil phosphate-038 | 103775-61-7 | (2R)-2-Hydroxypropyl 4-methylbenzene-1-sulfonate |
OptimisedRoute 6Steps 4 · Total yield /
Tenofovir disoproxil phosphate-0174254-14-2Tenofovir disoproxil phosphate-0391648543-28-5Tenofovir disoproxil phosphate-040685-83-6Tenofovir disoproxil phosphate-0411647147-88-3Tenofovir disoproxil phosphate-00873-24-5Tenofovir disoproxil phosphate-0421664338-79-7API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-017 | 4254-14-2 | Propane-1,2(R)-diol |
| Tenofovir disoproxil phosphate-039 | 1648543-28-5 | (4R)-4-Methyl-1,3-dioxolane |
| Tenofovir disoproxil phosphate-040 | 685-83-6 | N,N,N',N'-Tetraethylphosphorodiamidous chloride |
| Tenofovir disoproxil phosphate-041 | 1647147-88-3 | P-([[(2R)-1-Chloropropan-2-yl]oxy]methyl)-N,N,N',N'-tetraethylphosphonic diamide |
| Tenofovir disoproxil phosphate-008 | 73-24-5 | 6-Aminopurine |
| Tenofovir disoproxil phosphate-042 | 1664338-79-7 | P-([[(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)-N,N,N',N'-tetraethylphosphonic diamide |
OptimisedRoute 7Steps 3 · Total yield /
Tenofovir disoproxil phosphate-01414047-28-0Tenofovir disoproxil phosphate-00331618-90-3Tenofovir disoproxil phosphate-009180587-75-1Tenofovir disoproxil phosphate-04357-13-6Tenofovir disoproxil phosphate-04462-56-6Tenofovir disoproxil phosphate-045113-00-8Tenofovir disoproxil phosphate-046—Tenofovir disoproxil phosphate-0472035468-75-6Tenofovir disoproxil phosphate-048—API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-014 | 14047-28-0 | (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol |
| Tenofovir disoproxil phosphate-003 | 31618-90-3 | (Diethoxyphosphoryl)methyl 4-methylbenzene-1-sulfonate |
| Tenofovir disoproxil phosphate-009 | 180587-75-1 | (R)-9-[2-(Diethylphosphonomethoxy)propyl] adenine |
| Tenofovir disoproxil phosphate-043 | 57-13-6 | Carbamide |
| Tenofovir disoproxil phosphate-044 | 62-56-6Available | Thiocarbamide |
| Tenofovir disoproxil phosphate-045 | 113-00-8 | Guanidine |
| Tenofovir disoproxil phosphate-046 | - | Ethoxy(imino)methanaminium ethyl ([[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonate |
| Tenofovir disoproxil phosphate-047 | 2035468-75-6 | (Ethylsulfanyl)(imino)methanaminium ethyl ([[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonate |
| Tenofovir disoproxil phosphate-048 | - | (Ethylamino)(imino)methanaminium ethyl ([[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonate |
OptimisedRoute 8Steps 1 · Total yield 112.26g(Tenofovir disoproxil phosphate-051)
Tenofovir disoproxil phosphate-049206184-49-8,147127-20-6,147127-19-3Tenofovir disoproxil phosphate-050101-02-0Tenofovir disoproxil phosphate-051379270-35-6Tenofovir disoproxil phosphate-05266003-76-7Tenofovir disoproxil phosphate-053201358-23-8Tenofovir disoproxil phosphate-054313-39-3Tenofovir disoproxil phosphate-05558109-40-3Tenofovir disoproxil phosphate-05662613-15-4Tenofovir disoproxil phosphate-057722-56-5Tenofovir disoproxil phosphate-058322-23-6Tenofovir disoproxil phosphate-059—API · Lamivudine/Tenofovir Disoproxil Fumarate
| Code | CAS No. | Intermediate |
|---|---|---|
| Tenofovir disoproxil phosphate-049 | 206184-49-8,147127-20-6,147127-19-3 | ([[(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonic acid |
| Tenofovir disoproxil phosphate-050 | 101-02-0 | Phenyl phosphite |
| Tenofovir disoproxil phosphate-051 | 379270-35-6 | Phenyl hydrogen ([[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy]methyl)phosphonate |
| Tenofovir disoproxil phosphate-052 | 66003-76-7 | Diphenyliodanium trifluoromethanesulfonate |
| Tenofovir disoproxil phosphate-053 | 201358-23-8 | Diphenyliodanium methanesulfonate |
| Tenofovir disoproxil phosphate-054 | 313-39-3 | Diphenyliodanium tetrafluoridoborate(1-) |
| Tenofovir disoproxil phosphate-055 | 58109-40-3 | Diphenyliodonium hexafluorophosphate |
| Tenofovir disoproxil phosphate-056 | 62613-15-4 | Diphenyliodanium hexafluoridoarsenate(1-) |
| Tenofovir disoproxil phosphate-057 | 722-56-5 | Diphenyliodanium nitrate |
| Tenofovir disoproxil phosphate-058 | 322-23-6 | Diphenyliodanium fluoride |
| Tenofovir disoproxil phosphate-059 | - | Diphenyliodanium bromide |
Frequently asked questions
What are the approved indications of Lamivudine/Tenofovir Disoproxil Fumarate?
Approved indications include: HIV infection, Chronic hepatitis B.
When does the Lamivudine/Tenofovir Disoproxil Fumarate patent expire?
No public expiry year is available for Lamivudine/Tenofovir Disoproxil Fumarate yet; this page updates once verified.
How many synthesis routes are recorded for Lamivudine/Tenofovir Disoproxil Fumarate?
13 synthesis routes are recorded; the shortest is 1 steps with 112.26g(Tenofovir disoproxil phosphate-051) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Lamivudine/Tenofovir Disoproxil Fumarate intermediates?
5 intermediate CAS of Lamivudine/Tenofovir Disoproxil Fumarate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Lamivudine/Tenofovir Disoproxil Fumarate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29