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Capmatinib Hydrochloride

Tier C — Watch / trade

Capmatinib Hydrochloride · all drugs expiring in 2032 →

Incyte Corp
Originator
2020
First approval
2032
Expiry (public)
$0.15B ▲
Peak sales
Small molecule
Type

Targets:c-Met

Brand:Tabrecta

Indications (approved):Non-small cell lung cancer

Regional status

US
Approved
2020-05-06
EU
Approved
2022-06-20
China
Approved
2024-06-11
Japan
Approved
2020-06-29

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 12 · Total yield 260 mg
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
CAPMA-001153556-42-4Available4-bromo-3-fluorobenzoic acid
CAPMA-002695188-21-7Available4-bromo-3-fluorobenzoyl chloride
CAPMA-003343564-56-7Available4-bromo-3-fluoro-N-methoxy-N-methylbenzamide
CAPMA-004304445-49-6Available1-(4-bromo-3-fluorophenyl)ethanone
CAPMA-0051006875-89-3Available1-(4-bromo-3-fluorophenyl)-2,2-dihydroxyethanone
CAPMA-0061029714-83-7Available2-(4-bromo-3-fluorophenyl)-2-oxoacetaldehyde
CAPMA-0071006875-90-6Available1-(4-bromo-3-fluorophenyl)-2,2-diethoxyethanone
CAPMA-0082200-97-7Available-
CAPMA-0091029714-84-8Available6-(4-bromo-3-fluorophenyl)-1,2,4-triazin-3-amine
CAPMA-0101029714-85-9Available2-chloro-3-(quinolin-6-yl)propanal
CAPMA-0111029714-86-0Available6-((2-(4-bromo-3-fluorophenyl)imidazo[1,2-b][1,2,4]triazin-7-yl)methyl)quinoline
CAPMA-0121029714-87-1Available2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzonitrile
CAPMA-0131029714-88-2Available2-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzoic acid
CAPMA-0145332-25-2Available6-bromoquinoline
CAPMA-015476660-18-1Available3-(quinolin-6-yl)propanal
Capmatinib1029712-80-8Available2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide

Frequently asked questions

What are the approved indications of Capmatinib Hydrochloride?

Approved indications include: Non-small cell lung cancer.

When does the Capmatinib Hydrochloride patent expire?

Based on public sources, the Capmatinib Hydrochloride patent expires in 2032.

How many synthesis routes are recorded for Capmatinib Hydrochloride?

1 synthesis routes are recorded; the shortest is 12 steps with 260 mg total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Capmatinib Hydrochloride intermediates?

16 intermediate CAS of Capmatinib Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Capmatinib Hydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29