Zolmitriptan
Tier C — Watch / tradeZolmitriptan
Targets：5-HT1B, 5-HT1A, 5-HT1D
Brand：Zolmitriptan RapidFilm, Zomigon, Flezol, Zomig, AscoTop
Indications (approved)：Migraine
Regional status
Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ZOLM-001 | 949-99-5 | (S)-2-amino-3-(4-nitrophenyl)propanoic acid |
| ZOLM-002 | 81677-60-3 | methyl (S)-2-amino-3-(4-nitrophenyl)propanoate |
| ZOLM-003 | 89288-22-2 | (S)-2-amino-3-(4-nitrophenyl)propan-1-ol |
| ZOLM-004 | 139264-55-4 | (S)-4-(4-nitrobenzyl)oxazolidin-2-one |
| ZOLM-005 | 152305-23-2 | (S)-4-(4-aminobenzyl)oxazolidin-2-one |
| ZOLM-006 | 187975-62-8 | (S)-4-(4-hydrazinylbenzyl)oxazolidin-2-one |
| ZOLM-007 | 6139-83-9 | 4-chloro-1,1-diethoxybutane |
| ZOLM-008 | 139264-15-6 | (S)-4-((3-(2-aminoethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| ZOLM-016 | 1116-77-4 | 4,4-diethoxy-N,N-dimethylbutan-1-amine |
| ZOLM-017 | 106-40-1Available | 4-bromoaniline |
| ZOLM-018 | 622-88-8 | (4-bromophenyl)hydrazine |
| ZOLM-019 | 17274-65-6 | 2-(5-bromo-1H-indol-3-yl)-N,N-dimethylethan-1-amine |
| ZOLM-020 | 35356-70-8 | methyl 2-acetamidoacrylate |
| ZOLM-021 | 1241387-60-9 | methyl (Z)-2-acetamido-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)acrylate |
| ZOLM-022 | 1241387-61-0 | methyl (S)-2-acetamido-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)propanoate |
| ZOLM-023 | 1241387-62-1 | (S)-N-(1-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-3-hydroxypropan-2-yl)acetamide |
| ZOLM-024 | - | (S)-2-amino-3-(3-(2-aminoethyl)-1H-indol-5-yl)propan-1-ol hydrochloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| ZOLM-005 | 152305-23-2 | (S)-4-(4-aminobenzyl)oxazolidin-2-one |
| ZOLM-009 | - | (S,E)-4-(4-(chlorodiazenyl)benzyl)oxazolidin-2-one |
| ZOLM-010 | 55747-45-0 | ethyl 2-acetyl-5-(1,3-dioxoisoindolin-2-yl)pentanoate |
| ZOLM-011 | 868622-21-3 | ethyl (S)-3-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate |
| ZOLM-012 | 868622-22-4 | ethyl (S)-3-(2-aminoethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate hydrochloride |
| ZOLM-013 | 191864-24-1 | ethyl (S)-3-(2-aminoethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate hydrochloride |
| ZOLM-014 | 659738-69-9 | ethyl (S)-3-(2-(dimethylamino)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ZOLM-005 | 152305-23-2 | (S)-4-(4-aminobenzyl)oxazolidin-2-one |
| ZOLM-015 | 139264-57-6 | (S)-3-(2-(dimethylamino)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylic acid |
| ZOLM-016 | 1116-77-4 | 4,4-diethoxy-N,N-dimethylbutan-1-amine |
Frequently asked questions
What are the approved indications of Zolmitriptan?
Approved indications include: Migraine.
When does the Zolmitriptan patent expire?
No public expiry year is available for Zolmitriptan yet; this page updates once verified.
How many synthesis routes are recorded for Zolmitriptan?
4 synthesis routes are recorded; the shortest is 2 steps with 8.20 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Zolmitriptan intermediates?
1 intermediate CAS of Zolmitriptan are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Zolmitriptan intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29