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Valsartan/Lercanidipine Hydrochloride
Tier C — Watch / tradeValsartan/Lercanidipine Hydrochloride
Lg Chemical Ltd
Originator
2013
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type
Targets：AT1, VDCCs
Brand：Levacalm
Indications (approved)：Essential hypertension
Regional status
US
-
EU
-
China
-
Japan
-
Factories producing this API11
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
11 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates17 routes
Originator routes × 1Optimised (non-patent) × 16Process routes × 0
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
OriginatorRoute 1Steps 5 · Total yield /
VALS-001114772-54-2VALS-002154709-19-0VALS-003135689-93-9VALS-0046306-52-1VALS-005137863-89-9VALS-006638-29-9VALS-007137863-90-2API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-001 | 114772-54-2 | 4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile |
| VALS-002 | 154709-19-0 | 4'-(hydroxymethyl)-[1,1'-biphenyl]-2-carbonitrile |
| VALS-003 | 135689-93-9 | 4'-formyl-[1,1'-biphenyl]-2-carbonitrile |
| VALS-004 | 6306-52-1 | methyl L-valinate hydrochloride |
| VALS-005 | 137863-89-9 | (S)-methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate |
| VALS-006 | 638-29-9 | pentanoyl chloride |
| VALS-007 | 137863-90-2 | (S)-methyl 2-(N-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate |
OptimisedRoute 2Steps 3 · Total yield /
VALS-008151052-40-3VALS-00972-18-4VALS-010676129-91-2VALS-011676129-92-3API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-008 | 151052-40-3 | 2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde |
| VALS-009 | 72-18-4 | (S)-2-amino-3-methylbutanoic acid |
| VALS-010 | 676129-91-2 | (S,Z)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methylene)amino)-3-methylbutanoic acid |
| VALS-011 | 676129-92-3 | (S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoic acid |
OptimisedRoute 3Steps 3 · Total yield /
VALS-0046306-52-1VALS-006638-29-9VALS-012589-15-1VALS-013867022-53-5VALS-014918447-44-6VALS-015144873-97-2VALS-016781664-81-1API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-004 | 6306-52-1 | methyl L-valinate hydrochloride |
| VALS-006 | 638-29-9 | pentanoyl chloride |
| VALS-012 | 589-15-1 | 1-bromo-4-(bromomethyl)benzene |
| VALS-013 | 867022-53-5 | (S)-methyl 2-((4-bromobenzyl)amino)-3-methylbutanoate |
| VALS-014 | 918447-44-6 | (S)-methyl 2-(N-(4-bromobenzyl)pentanamido)-3-methylbutanoate |
| VALS-015 | 144873-97-2 | (2-(1-trityl-1H-tetrazol-5-yl)phenyl)boronic acid |
| VALS-016 | 781664-81-1 | (S)-methyl 3-methyl-2-(N-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)butanoate |
OptimisedRoute 1Steps 9 · Total yield /
Lercanidipine Hydrochloride-001674-82-8Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-003100427-51-8Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-005100427-54-1Lercanidipine Hydrochloride-00614205-39-1Lercanidipine Hydrochloride-00774936-72-4API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-001 | 674-82-8Available | 4-Methylene-2-oxetanone |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-003 | 100427-51-8 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl 3-oxobutanoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-005 | 100427-54-1 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl (2Z)-2-[(3-nitrophenyl)methylidene]-3-oxobutanoate |
| Lercanidipine Hydrochloride-006 | 14205-39-1 | 3-Amino-2-butenoic acid methyl ester |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
OptimisedRoute 2Steps 3 · Total yield /
Lercanidipine Hydrochloride-008105-45-3Lercanidipine Hydrochloride-009558-42-9Lercanidipine Hydrochloride-010—Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-011—Lercanidipine Hydrochloride-00614205-39-1Lercanidipine Hydrochloride-012890045-70-2Lercanidipine Hydrochloride-013890045-71-3Lercanidipine Hydrochloride-00774936-72-4Lercanidipine Hydrochloride-01488712-56-5Lercanidipine Hydrochloride-01538254-49-8Lercanidipine Hydrochloride-01628075-29-8API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-008 | 105-45-3Available | 1-Methoxybutane-1,3-dione |
| Lercanidipine Hydrochloride-009 | 558-42-9 | 1-Chloro-2-methyl-2-propanol |
| Lercanidipine Hydrochloride-010 | - | 1-Chloro-2-methylpropan-2-yl 3-oxobutanoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-011 | - | 1-Chloro-2-methylpropan-2-yl (2Z)-2-[(3-nitrophenyl)methylidene]-3-oxobutanoate |
| Lercanidipine Hydrochloride-006 | 14205-39-1 | 3-Amino-2-butenoic acid methyl ester |
| Lercanidipine Hydrochloride-012 | 890045-70-2 | 3-(1-Chloro-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-013 | 890045-71-3 | 3-(1-Bromo-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
| Lercanidipine Hydrochloride-014 | 88712-56-5 | 5-(Chlorocarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid methyl ester |
| Lercanidipine Hydrochloride-015 | 38254-49-8 | 1-Bromo-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-016 | 28075-29-8 | (3,3-Diphenylpropyl)(methyl)amine |
OptimisedRoute 3Steps 2 · Total yield /
Lercanidipine Hydrochloride-01628075-29-8Lercanidipine Hydrochloride-017105-53-3Lercanidipine Hydrochloride-01891-01-0Lercanidipine Hydrochloride-019—Lercanidipine Hydrochloride-020—Lercanidipine Hydrochloride-02174-89-5Lercanidipine Hydrochloride-022348607-76-1API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-016 | 28075-29-8 | (3,3-Diphenylpropyl)(methyl)amine |
| Lercanidipine Hydrochloride-017 | 105-53-3Available | 1,3-Diethyl propanedioate |
| Lercanidipine Hydrochloride-018 | 91-01-0 | 1,1-Diphenylmethanol |
| Lercanidipine Hydrochloride-019 | - | Diethyl (diphenylmethyl)propanedioate |
| Lercanidipine Hydrochloride-020 | - | Ethyl 3,3-diphenylpropanoate |
| Lercanidipine Hydrochloride-021 | 74-89-5 | Methylamine |
| Lercanidipine Hydrochloride-022 | 348607-76-1 | N-Methyl-3,3-diphenylpropanamide |
OptimisedRoute 4Steps 4 · Total yield /
Lercanidipine Hydrochloride-01628075-29-8Lercanidipine Hydrochloride-009558-42-9Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-023936491-32-6Lercanidipine Hydrochloride-00774936-72-4API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-016 | 28075-29-8 | (3,3-Diphenylpropyl)(methyl)amine |
| Lercanidipine Hydrochloride-009 | 558-42-9 | 1-Chloro-2-methyl-2-propanol |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-023 | 936491-32-6 | (2-chloro-2-methylpropyl)(3,3-diphenylpropyl)methylamine |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
OptimisedRoute 5Steps 4 · Total yield /
Lercanidipine Hydrochloride-00774936-72-4Lercanidipine Hydrochloride-01488712-56-5Lercanidipine Hydrochloride-024—Lercanidipine Hydrochloride-025887769-40-6Lercanidipine Hydrochloride-02620017-67-8Lercanidipine Hydrochloride-02723808-47-1Lercanidipine Hydrochloride-028957215-03-1API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
| Lercanidipine Hydrochloride-014 | 88712-56-5 | 5-(Chlorocarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid methyl ester |
| Lercanidipine Hydrochloride-024 | - | 2-Methyl-1-(methylamino)propan-2-ol p-toluenesulfonate |
| Lercanidipine Hydrochloride-025 | 887769-40-6 | 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 1,1-dimethyl-2-(methylamino)ethyl methyl ester |
| Lercanidipine Hydrochloride-026 | 20017-67-8 | 3,3-Diphenylpropan-1-ol |
| Lercanidipine Hydrochloride-027 | 23808-47-1 | 4-Methylbenzenesulfonic acid 3,3-diphenylpropyl ester |
| Lercanidipine Hydrochloride-028 | 957215-03-1 | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 2-[N-(3,3-diphenylpropyl)-N-methylamino]-1,1-dimethylethyl methyl diester oxalate |
OptimisedRoute 6Steps 5 · Total yield /
Lercanidipine Hydrochloride-029140-10-3Lercanidipine Hydrochloride-030102-92-1Lercanidipine Hydrochloride-02174-89-5Lercanidipine Hydrochloride-0312757-10-0Lercanidipine Hydrochloride-03271-43-2Lercanidipine Hydrochloride-022348607-76-1Lercanidipine Hydrochloride-01628075-29-8Lercanidipine Hydrochloride-009558-42-9Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-033—Lercanidipine Hydrochloride-00774936-72-4API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-029 | 140-10-3 | 3-Phenyl-2(E)-propenoic acid |
| Lercanidipine Hydrochloride-030 | 102-92-1 | (2E)-3-phenylprop-2-enoyl chloride |
| Lercanidipine Hydrochloride-021 | 74-89-5 | Methylamine |
| Lercanidipine Hydrochloride-031 | 2757-10-0 | N-Methyl-3-phenylacrylamide |
| Lercanidipine Hydrochloride-032 | 71-43-2 | Benzene |
| Lercanidipine Hydrochloride-022 | 348607-76-1 | N-Methyl-3,3-diphenylpropanamide |
| Lercanidipine Hydrochloride-016 | 28075-29-8 | (3,3-Diphenylpropyl)(methyl)amine |
| Lercanidipine Hydrochloride-009 | 558-42-9 | 1-Chloro-2-methyl-2-propanol |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-033 | - | Methyl 5-[[(diethoxyphosphoryl)oxy]carbonyl]-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
OptimisedRoute 7Steps 9 · Total yield /
Lercanidipine Hydrochloride-001674-82-8Lercanidipine Hydrochloride-034109-78-4Lercanidipine Hydrochloride-03565193-87-5Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-00614205-39-1Lercanidipine Hydrochloride-03675130-24-4Lercanidipine Hydrochloride-00774936-72-4Lercanidipine Hydrochloride-002100442-33-9API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-001 | 674-82-8Available | 4-Methylene-2-oxetanone |
| Lercanidipine Hydrochloride-034 | 109-78-4Available | 1-Cyano-2-hydroxyethane |
| Lercanidipine Hydrochloride-035 | 65193-87-5Available | 2-Cyanoethyl 3-oxobutanoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-006 | 14205-39-1 | 3-Amino-2-butenoic acid methyl ester |
| Lercanidipine Hydrochloride-036 | 75130-24-4 | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(2-cyanoethyl)5-methyl ester |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
OptimisedRoute 8Steps 3 · Total yield /
Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-0375394-63-8Lercanidipine Hydrochloride-038—Lercanidipine Hydrochloride-003100427-51-8Lercanidipine Hydrochloride-039—Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-008105-45-3Lercanidipine Hydrochloride-04039562-17-9API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-037 | 5394-63-8Available | 2,2,4-Trimethyl-6-keto-1,3-dioxin |
| Lercanidipine Hydrochloride-038 | - | 3-Oxobutanoyl chloride |
| Lercanidipine Hydrochloride-003 | 100427-51-8 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl 3-oxobutanoate |
| Lercanidipine Hydrochloride-039 | - | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl (2E)-3-aminobut-2-enoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-008 | 105-45-3Available | 1-Methoxybutane-1,3-dione |
| Lercanidipine Hydrochloride-040 | 39562-17-9 | (Z)-2-Acetyl-3-(3-nitrophenyl)acrylic acid methyl ester |
OptimisedRoute 9Steps 2 · Total yield /
Lercanidipine Hydrochloride-04121881-77-6Lercanidipine Hydrochloride-04274936-81-5API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-041 | 21881-77-6 | Dimethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-042 | 74936-81-5 | 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid |
OptimisedRoute 10Steps 4 · Total yield /
Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-008105-45-3Lercanidipine Hydrochloride-04321731-17-9Lercanidipine Hydrochloride-04121881-77-6Lercanidipine Hydrochloride-00774936-72-4Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-044100427-26-7Lercanidipine Hydrochloride-01488712-56-5Lercanidipine Hydrochloride-01628075-29-8Lercanidipine Hydrochloride-009558-42-9API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-008 | 105-45-3Available | 1-Methoxybutane-1,3-dione |
| Lercanidipine Hydrochloride-043 | 21731-17-9 | (Z)-Methyl 3-aminobut-2-enoate |
| Lercanidipine Hydrochloride-041 | 21881-77-6 | Dimethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-007 | 74936-72-4 | (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-044 | 100427-26-7 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-014 | 88712-56-5 | 5-(Chlorocarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid methyl ester |
| Lercanidipine Hydrochloride-016 | 28075-29-8 | (3,3-Diphenylpropyl)(methyl)amine |
| Lercanidipine Hydrochloride-009 | 558-42-9 | 1-Chloro-2-methyl-2-propanol |
OptimisedRoute 11Steps 4 · Total yield /
Lercanidipine Hydrochloride-045141-97-9Lercanidipine Hydrochloride-034109-78-4Lercanidipine Hydrochloride-03565193-87-5Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-04675130-34-6Lercanidipine Hydrochloride-04274936-81-5API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-045 | 141-97-9Available | Acetoacetic ethyl ester |
| Lercanidipine Hydrochloride-034 | 109-78-4Available | 3-Hydroxypropionitrile |
| Lercanidipine Hydrochloride-035 | 65193-87-5Available | 2-Cyanoethyl 3-oxobutanoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | m-Nitrobenzaldehyde |
| Lercanidipine Hydrochloride-046 | 75130-34-6 | Bis(2-cyanoethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Lercanidipine Hydrochloride-042 | 74936-81-5 | 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid |
OptimisedRoute 12Steps 5 · Total yield /
Lercanidipine Hydrochloride-008105-45-3Lercanidipine Hydrochloride-002100442-33-9Lercanidipine Hydrochloride-003100427-51-8Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-005100427-54-1Lercanidipine Hydrochloride-00614205-39-1Lercanidipine Hydrochloride-044100427-26-7API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-008 | 105-45-3Available | 1-Methoxybutane-1,3-dione |
| Lercanidipine Hydrochloride-002 | 100442-33-9 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol |
| Lercanidipine Hydrochloride-003 | 100427-51-8 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl 3-oxobutanoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | (3-Nitrophenyl)methanone |
| Lercanidipine Hydrochloride-005 | 100427-54-1 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl (2Z)-2-[(3-nitrophenyl)methylidene]-3-oxobutanoate |
| Lercanidipine Hydrochloride-006 | 14205-39-1 | 3-Amino-2-butenoic acid methyl ester |
| Lercanidipine Hydrochloride-044 | 100427-26-7 | 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
OptimisedRoute 13Steps 4 · Total yield /
Lercanidipine Hydrochloride-04798-86-2Lercanidipine Hydrochloride-048593-51-1Lercanidipine Hydrochloride-04927152-62-1Lercanidipine Hydrochloride-05042142-52-9Lercanidipine Hydrochloride-03271-43-2Lercanidipine Hydrochloride-051—API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-047 | 98-86-2 | 1-Phenylethan-1-one |
| Lercanidipine Hydrochloride-048 | 593-51-1 | Methanamine hydrochloride |
| Lercanidipine Hydrochloride-049 | 27152-62-1 | 3-(Methylamino)-1-phenylpropan-1-one |
| Lercanidipine Hydrochloride-050 | 42142-52-9 | (+/-)-n-Methyl-3-hydroxy-3-phenylpropylamine |
| Lercanidipine Hydrochloride-032 | 71-43-2 | Benzene |
| Lercanidipine Hydrochloride-051 | - | N-(3,3-Diphenylpropyl)-N-methylamine hydrochloride |
OptimisedRoute 14Steps 5 · Total yield /
Lercanidipine Hydrochloride-008105-45-3Lercanidipine Hydrochloride-034109-78-4Lercanidipine Hydrochloride-03565193-87-5Lercanidipine Hydrochloride-052—Lercanidipine Hydrochloride-00499-61-6Lercanidipine Hydrochloride-03675130-24-4API · Valsartan/Lercanidipine Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Lercanidipine Hydrochloride-008 | 105-45-3Available | Methyl acetoacetate |
| Lercanidipine Hydrochloride-034 | 109-78-4Available | 3-Hydroxypropionitrile |
| Lercanidipine Hydrochloride-035 | 65193-87-5Available | 2-Cyanoethyl 3-oxobutanoate |
| Lercanidipine Hydrochloride-052 | - | (E)-2-cyanoethyl 3-aminobut-2-enoate |
| Lercanidipine Hydrochloride-004 | 99-61-6 | 3-Nitrobenzaldehyde |
| Lercanidipine Hydrochloride-036 | 75130-24-4 | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-Methyl E |
Frequently asked questions
What are the approved indications of Valsartan/Lercanidipine Hydrochloride?
Approved indications include: Essential hypertension.
When does the Valsartan/Lercanidipine Hydrochloride patent expire?
No public expiry year is available for Valsartan/Lercanidipine Hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Valsartan/Lercanidipine Hydrochloride?
17 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Valsartan/Lercanidipine Hydrochloride intermediates?
7 intermediate CAS of Valsartan/Lercanidipine Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Valsartan/Lercanidipine Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29