Cariprazine Hydrochloride
Tier A — Act nowCariprazine Hydrochloride · all drugs expiring in 2029 →
Targets：5-HT2A, 5-HT1A, DRD2, DRD3, HRH1, 5-HT2B
Brand：Vraylar, Reagila
Indications (approved)：Major depressive disorder, Schizophrenia, Mania
Regional status
Factories producing this API1
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
1 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-001 | 56961-77-4 | 1-bromo-2,3-dichlorobenzene |
| CARI-002 | 57260-71-6Available | tert-butyl piperazine-1-carboxylate |
| CARI-003 | 503315-03-5 | tert-butyl 4-(2,3-dichlorophenyl)piperazine-1-carboxylate |
| CARI-004 | 119532-26-2Available | 1-(2,3-dichlorophenyl)piperazine hydrochloride |
| CARI-005 | 215790-29-7 | tert-butyl ((1r,4r)-4-(2-oxoethyl)cyclohexyl)carbamate |
| CARI-006 | 506427-91-4 | tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate |
| CARI-007 | 791778-53-5 | (1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine |
| CARI-008 | 79-44-7 | dimethylcarbamic chloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-008 | 79-44-7 | dimethylcarbamic chloride |
| CARI-009 | 87976-86-1 | 4-aminocyclohexanone |
| CARI-010 | 1512029-27-4 | 1,1-dimethyl-3-(4-oxocyclohexyl)urea |
| CARI-011 | 867-13-0Available | ethyl 2-(diethoxyphosphoryl)acetate |
| CARI-012 | 1698050-47-3 | ethyl 2-(4-(3,3-dimethylureido)cyclohexylidene)acetate |
| CARI-013 | 1642586-63-7 | ethyl 2-((1r,4r)-4-(3,3-dimethylureido)cyclohexyl)acetate |
| CARI-014 | 1698050-40-6 | 3-((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)-1,1-dimethylurea |
| CARI-015 | 1642586-58-0 | 1,1-dimethyl-3-((1r,4r)-4-(2-oxoethyl)cyclohexyl)urea |
| CARI-016 | 41202-77-1Available | 1-(2,3-dichlorophenyl)piperazine |
| Code | CAS No. | Intermediate |
|---|---|---|
| CARI-006 | 506427-91-4 | tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate |
| CARI-016 | 41202-77-1Available | 1-(2,3-dichlorophenyl)piperazine |
| CARI-017 | 104-03-0 | 2-(4-nitrophenyl)acetic acid |
| CARI-018 | 113543-96-7 | ethyl 2-((1r,4r)-4-aminocyclohexyl)acetate hydrochloride |
| CARI-019 | 946598-34-1 | ethyl 2-((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)acetate |
| CARI-020 | 917342-29-1 | tert-butyl ((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)carbamate |
| CARI-021 | 791778-53-5 | (1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine |
| CARI-022 | 1702725-92-5 | N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1H-imidazole-1-carboxamide |
Frequently asked questions
What are the approved indications of Cariprazine Hydrochloride?
Approved indications include: Major depressive disorder, Schizophrenia, Mania.
When does the Cariprazine Hydrochloride patent expire?
Based on public sources, the Cariprazine Hydrochloride patent expires in 2029.
How many synthesis routes are recorded for Cariprazine Hydrochloride?
3 synthesis routes are recorded; the shortest is 5 steps with 0.83 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Cariprazine Hydrochloride intermediates?
4 intermediate CAS of Cariprazine Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Cariprazine Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29