Apinocaltamide
Tier C — Watch / tradeApinocaltamide
Targets：T-channels
Indications (approved)：脑疾病, 特发性震颤, 反射性癫痫
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ACT-709478-001 | 158626-15-4 | 6-(bromomethyl)nicotinonitrile |
| ACT-709478-002 | 26621-44-3 | 3-nitro-1H-pyrazole |
| ACT-709478-003 | 1838653-23-8 | 6-((3-nitro-1H-pyrazol-1-yl)methyl)nicotinonitrile |
| ACT-709478-004 | 1838633-02-5 | 6-((3-amino-1H-pyrazol-1-yl)methyl)nicotinonitrile |
| ACT-709478-005 | 1838654-62-8 | 2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetic acid |
| ACT-709478-006 | 1227160-18-0 | 1-bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene |
| ACT-709478-007 | 321745-86-2 | (2-(tert-butoxy)-2-oxoethyl)zinc(II) chloride |
| ACT-709478-008 | 1838654-61-7 | tert-butyl 2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetate |
Frequently asked questions
What are the approved indications of Apinocaltamide?
Approved indications include: 脑疾病, 特发性震颤, 反射性癫痫.
When does the Apinocaltamide patent expire?
No public expiry year is available for Apinocaltamide yet; this page updates once verified.
How many synthesis routes are recorded for Apinocaltamide?
1 synthesis routes are recorded; the shortest is 5 steps with 10.7 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Apinocaltamide intermediates?
All intermediates in Apinocaltamide routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Apinocaltamide intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-09