Tolfenamic Acid
Tier C — Watch / tradeTolfenamic Acid
Targets：COXs
Brand：Clotam, Migea
Indications (approved)：Arthritis, Migraine, Pain, Dysmenorrhoea
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Tolfenamic Acid-001 | 118-91-2 | 2-Chlorobenzoic acid |
| Tolfenamic Acid-002 | 17264-74-3 | Sodium 2-chlorobenzoate |
| Tolfenamic Acid-003 | - | 2-Chlorobenoic acid potassium salt |
| Tolfenamic Acid-004 | 87-60-5 | 2-Amino-6-chlorotoluene |
| Tolfenamic Acid-005 | 88-65-3 | 2-Bromobenzoic acid |
| Tolfenamic Acid-006 | 16497-87-3 | 2-Bromobenzoic acid potassium salt |
| Code | CAS No. | Intermediate |
|---|---|---|
| Tolfenamic Acid-008 | 33757-48-1 | N-(Quinolin-8-yl)benzamide |
| Tolfenamic Acid-004 | 87-60-5 | 2-Amino-6-chlorotoluene |
| Tolfenamic Acid-009 | 1919043-43-8 | 2-(3-Chloro-2-methylanilino)-N-(quinolin-8-yl)benzamide |
Frequently asked questions
What are the approved indications of Tolfenamic Acid?
Approved indications include: Arthritis, Migraine, Pain, Dysmenorrhoea.
When does the Tolfenamic Acid patent expire?
No public expiry year is available for Tolfenamic Acid yet; this page updates once verified.
How many synthesis routes are recorded for Tolfenamic Acid?
3 synthesis routes are recorded; the shortest is 1 steps with 92g(Tolfenamic Acid (Free)) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Tolfenamic Acid intermediates?
All intermediates in Tolfenamic Acid routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Tolfenamic Acid intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29