Elismetrep
Tier C — Watch / tradeElismetrep
Targets：TRPM8
Indications (approved)：Migraine, 糖尿病周围神经病变, Hot flushes, Vasomotor symptoms
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ELISME-001 | 25475-67-6 | isoquinolin-3-amine |
| ELISME-002 | 10486-51-8 | ethyl 4-(chlorosulfonyl)benzoate |
| ELISME-003 | 1400702-32-0 | ethyl 4-(N-(isoquinolin-3-yl)sulfamoyl)benzoate |
| ELISME-004 | 1400702-33-1 | ethyl 4-(N-(4-iodoisoquinolin-3-yl)sulfamoyl)benzoate |
| ELISME-005 | 50824-05-0 | 1-(bromomethyl)-4-(trifluoromethoxy)benzene |
| ELISME-006 | 1400702-34-2 | ethyl 4-(N-(4-iodoisoquinolin-3-yl)-N-(4-(trifluoromethoxy)benzyl)sulfamoyl)benzoate |
| ELISME-007 | 411235-57-9 | cyclopropylboronic acid |
| ELISME-008 | 1400699-63-9 | ethyl 4-(N-(4-cyclopropylisoquinolin-3-yl)-N-(4-(trifluoromethoxy)benzyl)sulfamoyl)benzoate |
| Elismetrep | 1400699-64-0 | - |
Frequently asked questions
What are the approved indications of Elismetrep?
Approved indications include: Migraine, 糖尿病周围神经病变, Hot flushes, Vasomotor symptoms.
When does the Elismetrep patent expire?
No public expiry year is available for Elismetrep yet; this page updates once verified.
How many synthesis routes are recorded for Elismetrep?
1 synthesis routes are recorded; the shortest is 5 steps with 25.8 g (Elismetrep) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Elismetrep intermediates?
All intermediates in Elismetrep routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Elismetrep intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29