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Plazomicin sulfate

Tier C — Watch / trade

Plazomicin sulfate

Ionis Pharmaceuticals Inc
Originator
2018
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:30S subunit

Brand:Zemdri

Indications (approved):Bacterial infection, Hospital-acquired pneumonia, Urinary tract infection, Pyelonephritis, End-stage renal disease, 肠杆菌科感染, Ventilator-associated pneumonia, Healthcare-associated pneumonia

Regional status

US
Withdrawn
EU
-
China
-
Japan
-

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 9 · Total yield /
PLAZ-0011154758-54-9PLAZ-0021154758-55-0PLAZ-0031154758-58-3PLAZ-0041154758-59-4PLAZ-005207305-60-0PLAZ-0061154758-62-9PLAZ-0071154758-63-0PLAZ-008102191-92-4PLAZ-0091154758-74-3PLAZ-01040371-51-5API · Plazomicin sulfate
CodeCAS No.Intermediate
PLAZ-0011154758-54-9-
PLAZ-0021154758-55-0-
PLAZ-0031154758-58-3-
PLAZ-0041154758-59-4-
PLAZ-005207305-60-0(S)-4-((tert-butoxycarbonyl)amino)-2-hydroxybutanoic acid
PLAZ-0061154758-62-9-
PLAZ-0071154758-63-0-
PLAZ-008102191-92-42-((tert-butyldimethylsilyl)oxy)acetaldehyde
PLAZ-0091154758-74-3-
PLAZ-01040371-51-5(S)-4-amino-2-hydroxybutanoic acid
OptimisedRoute 2Steps 4 · Total yield /
PLAZ-01113139-17-8PLAZ-0121335436-86-6PLAZ-01340371-52-6PLAZ-0141335436-89-9PLAZ-01564904-47-8PLAZ-0161335436-90-2API · Plazomicin sulfate
CodeCAS No.Intermediate
PLAZ-01113139-17-8benzyl (2,5-dioxopyrrolidin-1-yl) carbonate
PLAZ-0121335436-86-6D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->6)-O-[2,3,4,6-tetradeoxy-...]-2-deoxy-N3-[(phenylmethoxy)carbonyl]-
PLAZ-01340371-52-6(S)-2,5-dioxopyrrolidin-1-yl 4-(((benzyloxy)carbonyl)amino)-2-hydroxybutanoate
PLAZ-0141335436-89-9-
PLAZ-01564904-47-82-oxoethyl benzoate
PLAZ-0161335436-90-22-((((2S,3R)-3-(((benzyloxy)carbonyl)amino)-2-(((1R,2S,3S,4R,6S)-6-(((benzyloxy)carbonyl)amino)-4-((S)-4-(((benzyloxy)carbonyl)amino)-2-hydroxybutanamido)-3-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,4-dihydro-2H-pyran-6-yl)methyl)amino)ethyl benzoate

Frequently asked questions

What are the approved indications of Plazomicin sulfate?

Approved indications include: Bacterial infection, Hospital-acquired pneumonia, Urinary tract infection, Pyelonephritis, End-stage renal disease, 肠杆菌科感染, Ventilator-associated pneumonia, Healthcare-associated pneumonia.

When does the Plazomicin sulfate patent expire?

No public expiry year is available for Plazomicin sulfate yet; this page updates once verified.

How many synthesis routes are recorded for Plazomicin sulfate?

2 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Plazomicin sulfate intermediates?

All intermediates in Plazomicin sulfate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Plazomicin sulfate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29