Unibest
← Back to patent-cliff list

Aclidinium Bromide/Formoterol Fumarate Dihydrate

Tier C — Watch / trade

Aclidinium Bromide/Formoterol Fumarate Dihydrate

AstraZeneca
Originator
2014
First approval
-
Expiry (public)
$0.1B ▲
Peak sales
Small molecule
Type

Targets:ADRB2, CHRM3

Brand:Duaklir Genuair, Brimica Genuair, Duaklir pressair

Indications (approved):Chronic obstructive pulmonary disease

Regional status

US
Approved
2019-03-29
EU
Approved
2014-11-19
China
Approved
2026-04-14
Japan
-

Factories producing this API12

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

12 producing factories on file — sign in to view the named list (factory details are not shown to guests).

Sign in to view factories →

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 7.2 g
ACLI-001553-90-2ACLI-0021003-09-4ACLI-00326447-85-8ACLI-00425333-42-0ACLI-005320347-97-5ACLI-006588-63-6API · Aclidinium Bromide/Formoterol Fumarate Dihydrate
CodeCAS No.Intermediate
ACLI-001553-90-2dimethyl oxalate
ACLI-0021003-09-42-bromothiophene
ACLI-00326447-85-8methyl 2-hydroxy-2,2-di(thiophen-2-yl)acetate
ACLI-00425333-42-0(R)-quinuclidin-3-ol
ACLI-005320347-97-5(1S,3R,4S)-quinuclidin-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate
ACLI-006588-63-6(3-bromopropoxy)benzene

Frequently asked questions

What are the approved indications of Aclidinium Bromide/Formoterol Fumarate Dihydrate?

Approved indications include: Chronic obstructive pulmonary disease.

When does the Aclidinium Bromide/Formoterol Fumarate Dihydrate patent expire?

No public expiry year is available for Aclidinium Bromide/Formoterol Fumarate Dihydrate yet; this page updates once verified.

How many synthesis routes are recorded for Aclidinium Bromide/Formoterol Fumarate Dihydrate?

1 synthesis routes are recorded; the shortest is 3 steps with 7.2 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Aclidinium Bromide/Formoterol Fumarate Dihydrate intermediates?

All intermediates in Aclidinium Bromide/Formoterol Fumarate Dihydrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Aclidinium Bromide/Formoterol Fumarate Dihydrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29