Valsartan
Tier B — Position earlyValsartan
Targets：AT1
Brand：Kalpress, Valpression, Varexan, Provas, Vals, Tareg, Diovan, Nisis, Miten
Indications (approved)：Left ventricular dysfunction, Hypertension
Regional status
Factories producing this API2
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
2 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-001 | 114772-54-2 | 4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile |
| VALS-002 | 154709-19-0 | 4'-(hydroxymethyl)-[1,1'-biphenyl]-2-carbonitrile |
| VALS-003 | 135689-93-9 | 4'-formyl-[1,1'-biphenyl]-2-carbonitrile |
| VALS-004 | 6306-52-1 | methyl L-valinate hydrochloride |
| VALS-005 | 137863-89-9 | (S)-methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate |
| VALS-006 | 638-29-9 | pentanoyl chloride |
| VALS-007 | 137863-90-2 | (S)-methyl 2-(N-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate |
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-008 | 151052-40-3 | 2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde |
| VALS-009 | 72-18-4 | (S)-2-amino-3-methylbutanoic acid |
| VALS-010 | 676129-91-2 | (S,Z)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methylene)amino)-3-methylbutanoic acid |
| VALS-011 | 676129-92-3 | (S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VALS-004 | 6306-52-1 | methyl L-valinate hydrochloride |
| VALS-006 | 638-29-9 | pentanoyl chloride |
| VALS-012 | 589-15-1 | 1-bromo-4-(bromomethyl)benzene |
| VALS-013 | 867022-53-5 | (S)-methyl 2-((4-bromobenzyl)amino)-3-methylbutanoate |
| VALS-014 | 918447-44-6 | (S)-methyl 2-(N-(4-bromobenzyl)pentanamido)-3-methylbutanoate |
| VALS-015 | 144873-97-2 | (2-(1-trityl-1H-tetrazol-5-yl)phenyl)boronic acid |
| VALS-016 | 781664-81-1 | (S)-methyl 3-methyl-2-(N-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)butanoate |
Frequently asked questions
What are the approved indications of Valsartan?
Approved indications include: Left ventricular dysfunction, Hypertension.
When does the Valsartan patent expire?
No public expiry year is available for Valsartan yet; this page updates once verified.
How many synthesis routes are recorded for Valsartan?
3 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Valsartan intermediates?
All intermediates in Valsartan routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Valsartan intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29