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PXS-4728

Tier C — Watch / trade

PXS-4728

Syntara Ltd
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:AOC3

Indications (approved):REM睡眠行为障碍, Diabetic retinopathy, Non-alcoholic steatohepatitis, Renal impairment

Regional status

US
No progress
2017-06-06
EU
Phase II
2017-06-06
China
-
Japan
No progress
2017-06-07

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 7 · Total yield /
PXS-4728—PXS-4728-001616-30-8PXS-4728-002195197-94-5PXS-4728-003184429-84-3PXS-4728-0042243825-08-1PXS-4728-0051478364-91-8PXS-4728-0061478364-89-4PXS-4728-007250656-24-7PXS-4728-0082209566-99-2API · PXS-4728
CodeCAS No.Intermediate
PXS-4728--
PXS-4728-001616-30-83-aminopropane-1,2-diol
PXS-4728-002195197-94-5tert-butyl (3-((tert-butyldimethylsilyl)oxy)-2-hydroxypropyl)carbamate
PXS-4728-003184429-84-3tert-butyl (3-((tert-butyldimethylsilyl)oxy)-2-oxopropyl)carbamate
PXS-4728-0042243825-08-1tert-butyl (2-(((tert-butyldimethylsilyl)oxy)methyl)-3-fluoroallyl)carbamate
PXS-4728-0051478364-91-8(E)-tert-butyl (3-fluoro-2-(hydroxymethyl)allyl)carbamate
PXS-4728-0061478364-89-4(E)-tert-butyl (2-(bromomethyl)-3-fluoroallyl)carbamate
PXS-4728-007250656-24-7N-(tert-butyl)-4-hydroxybenzamide
PXS-4728-0082209566-99-2(E)-tert-butyl (2-((4-(tert-butylcarbamoyl)phenoxy)methyl)-3-fluoroallyl)carbamate

Frequently asked questions

What are the approved indications of PXS-4728?

Approved indications include: REM睡眠行为障碍, Diabetic retinopathy, Non-alcoholic steatohepatitis, Renal impairment.

When does the PXS-4728 patent expire?

No public expiry year is available for PXS-4728 yet; this page updates once verified.

How many synthesis routes are recorded for PXS-4728?

1 synthesis routes are recorded; the shortest is 7 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy PXS-4728 intermediates?

All intermediates in PXS-4728 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for PXS-4728 intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-09