ivaltinostat
Tier C — Watch / tradeivaltinostat
Targets：HDAC
Indications (approved)：Pancreatic cancer, Myelodysplastic syndrome, Solid tumour, Fibrosis, Haematological malignancy
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CG-200745-001 | 502-44-3 | oxepan-2-one |
| CG-200745-002 | 4547-43-7 | methyl 6-hydroxyhexanoate |
| CG-200745-003 | 6654-36-0 | methyl 6-oxohexanoate |
| CG-200745-004 | 936221-70-4 | 1-(tert-butyl) 8-methyl 3-hydroxy-2-methyleneoctanedioate |
| CG-200745-005 | 936221-71-5 | 1-(tert-butyl) 8-methyl (Z)-2-(bromomethyl)oct-2-enedioate |
| CG-200745-006 | 90-15-3 | naphthalen-1-ol |
| CG-200745-007 | 936221-72-6 | 1-(tert-butyl) 8-methyl (E)-2-((naphthalen-1-yloxy)methyl)oct-2-enedioate |
| CG-200745-008 | 936221-69-1 | (E)-8-methoxy-2-((naphthalen-1-yloxy)methyl)-8-oxooct-2-enoic acid |
| CG-200745-009 | 109-55-7 | N1,N1-dimethylpropane-1,3-diamine |
| CG-200745-010 | 936222-18-3 | methyl (E)-8-((3-(dimethylamino)propyl)amino)-7-((naphthalen-1-yloxy)methyl)-8-oxooct-6-enoate |
| CG-200745-011 | 936222-19-4 | (E)-8-((3-(dimethylamino)propyl)amino)-7-((naphthalen-1-yloxy)methyl)-8-oxooct-6-enoic acid |
| CG-200745-012 | 6723-30-4 | O-(tetrahydro-2H-pyran-2-yl)hydroxylamine |
| CG-200745-013 | 936222-20-7 | (E)-N1-(3-(dimethylamino)propyl)-2-((naphthalen-1-yloxy)methyl)-N8-((tetrahydro-2H-pyran-2-yl)oxy)oct-2-enediamide |
Frequently asked questions
What are the approved indications of ivaltinostat?
Approved indications include: Pancreatic cancer, Myelodysplastic syndrome, Solid tumour, Fibrosis, Haematological malignancy.
When does the ivaltinostat patent expire?
No public expiry year is available for ivaltinostat yet; this page updates once verified.
How many synthesis routes are recorded for ivaltinostat?
1 synthesis routes are recorded; the shortest is 10 steps with 142 mg (CG-200745) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy ivaltinostat intermediates?
All intermediates in ivaltinostat routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for ivaltinostat intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-10