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Mifepristone

Tier C — Watch / trade

Mifepristone

Danco Laboratories LLC
Originator
1987
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PR

Brand:Pictovir, Mifeprex, Korlym, Corlux

Indications (approved):Cushing's syndrome, Termination of pregnancy

Regional status

US
Approved
2000-09-28
EU
Approved
1987-01-01
China
Approved
1995-01-01
Japan
-

Factories producing this API2

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 4 · Total yield 0.93 g
MIFE-0015571-36-8MIFE-00274-99-7MIFE-00384371-69-7MIFE-004684-16-2MIFE-00584371-57-3MIFE-0067353-91-5MIFE-007—API · Mifepristone
CodeCAS No.Intermediate
MIFE-0015571-36-8(8S,13S,14S)-13-methyl-1,4,6,7,8,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17(2H)-one
MIFE-00274-99-7prop-1-yne
MIFE-00384371-69-7(8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol
MIFE-004684-16-21,1,1,3,3,3-hexafluoropropan-2-one
MIFE-00584371-57-3(5'R,8'S,10'R,13'S,14'S,17'S)-13'-methyl-17'-(prop-1-yn-1-yl)-1',2',7',8',12',13',14',15',16',17'-decahydro-4'H,6'H-spiro[[1,3]dioxolane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-ol
MIFE-0067353-91-5(4-(dimethylamino)phenyl)magnesium bromide
MIFE-007-(8S,11R,13S,14S,17S)-11-(4-(dimethylamino)phenyl)-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol
OptimisedRoute 2Steps 2 · Total yield 22.50 g
MIFE-008510-64-5MIFE-0091562787-62-5MIFE-0105173-46-6API · Mifepristone
CodeCAS No.Intermediate
MIFE-008510-64-5(8R,13S,14S)-10-(hydroxymethyl)-13-methyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione
MIFE-0091562787-62-5(8S,13S,14S)-13-methyl-3,17-dioxo-1,2,3,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-10H-cyclopenta[a]phenanthren-10-yl acetate
MIFE-0105173-46-6(8S,13S,14S)-13-methyl-1,6,7,8,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione

Frequently asked questions

What are the approved indications of Mifepristone?

Approved indications include: Cushing's syndrome, Termination of pregnancy.

When does the Mifepristone patent expire?

No public expiry year is available for Mifepristone yet; this page updates once verified.

How many synthesis routes are recorded for Mifepristone?

2 synthesis routes are recorded; the shortest is 2 steps with 22.50 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Mifepristone intermediates?

All intermediates in Mifepristone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Mifepristone intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29