Lafutidine
Tier C — Watch / tradeLafutidine
Targets：HRH2
Brand：Protecadin, Stogar, Protecadin OD
Indications (approved)：Duodenal ulcer, Gastric ulcer, Gastro-oesophageal reflux disease, Peptic ulcer
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| LAFU-001 | 88046-02-0 | 2-bromo-4-(piperidin-1-ylmethyl)pyridine |
| LAFU-002 | 41372-34-3 | (Z)-4-aminobut-2-en-1-ol |
| LAFU-003 | 103922-84-5 | (Z)-4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-amine |
| LAFU-004 | 108499-26-9 | 2-((furan-2-ylmethyl)sulfinyl)acetic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| LAFU-005 | 118289-18-2 | 2-bromo-4-(1,3-dioxolan-2-yl)pyridine |
| LAFU-006 | 57323-06-5 | (Z)-4-((tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-ol |
| LAFU-007 | 118289-19-3 | (Z)-4-(1,3-dioxolan-2-yl)-2-((4-((tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-yl)oxy)pyridine |
| LAFU-008 | 118289-22-8 | (Z)-4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-amine |
| LAFU-009 | 123855-55-0 | 4-nitrophenyl 2-((furan-2-ylmethyl)sulfinyl)acetate |
| LAFU-010 | 118289-23-9 | (Z)-N-(4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-yl)-2-((furan-2-ylmethyl)sulfinyl)acetamide |
| LAFU-011 | 118287-95-9 | (Z)-N-(4-((4-formylpyridin-2-yl)oxy)but-2-en-1-yl)-2-((furan-2-ylmethyl)sulfinyl)acetamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| LAFU-003 | 103922-84-5 | (Z)-4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-amine |
| LAFU-009 | 123855-55-0 | 4-nitrophenyl 2-((furan-2-ylmethyl)sulfinyl)acetate |
| LAFU-012 | 1184963-60-7 | (Z)-2-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)isoindoline-1,3-dione maleate |
Frequently asked questions
What are the approved indications of Lafutidine?
Approved indications include: Duodenal ulcer, Gastric ulcer, Gastro-oesophageal reflux disease, Peptic ulcer.
When does the Lafutidine patent expire?
No public expiry year is available for Lafutidine yet; this page updates once verified.
How many synthesis routes are recorded for Lafutidine?
3 synthesis routes are recorded; the shortest is 2 steps with 0.18 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Lafutidine intermediates?
All intermediates in Lafutidine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Lafutidine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29