← Back to patent-cliff list

Crolibulin

Tier C — Watch / trade

Crolibulin

Immune Pharmaceuticals Inc
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:Tubulin

Indications (approved):Lymphoma, Anaplastic thyroid cancer, Solid tumour

Regional status

US
No progress
2011-01-26
EU
-
China
-
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield /
CROLI-0016948-30-7CROLI-002109-77-3CROLI-00359649-56-8CROLI-004475576-83-1Crolibulin—API · Crolibulin
CodeCAS No.Intermediate
CROLI-0016948-30-73-bromo-4,5-dimethoxybenzaldehyde
CROLI-002109-77-3Availablemalononitrile
CROLI-00359649-56-82,3-diaminophenol
CROLI-004475576-83-12,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-chromene-3-carbonitrile
Crolibulin-(R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-chromene-3-carbonitrile

Frequently asked questions

What are the approved indications of Crolibulin?

Approved indications include: Lymphoma, Anaplastic thyroid cancer, Solid tumour.

When does the Crolibulin patent expire?

No public expiry year is available for Crolibulin yet; this page updates once verified.

How many synthesis routes are recorded for Crolibulin?

1 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Crolibulin intermediates?

1 intermediate CAS of Crolibulin are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Crolibulin intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-19