Betrixaban
Tier C — Watch / tradeBetrixaban · all drugs expiring in 2028 →
Targets：F10
Brand：Bevyxxa
Indications (approved)：Venous thromboembolism, Hepatic function decline, Atrial fibrillation, Atrial flutter, Renal impairment, Thromboembolism
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| BETR-001 | 1882-69-5 | 5-methoxy-2-nitrobenzoic acid |
| BETR-002 | 1072-98-6 | 5-chloropyridin-2-amine |
| BETR-003 | 280773-16-2 | N-(5-chloropyridin-2-yl)-5-methoxy-2-nitrobenzamide |
| BETR-004 | 585544-20-3 | 6-chloro-N-neopentylnicotinamide |
| BETR-005 | 6068-72-0 | 4-cyanobenzoyl chloride |
| BETR-006 | 330942-01-3 | N-(5-chloropyridin-2-yl)-2-(4-cyanobenzamido)-5-methoxybenzamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| BETR-004 | 585544-20-3 | 6-chloro-N-neopentylnicotinamide |
| BETR-007 | 619-65-8 | 4-cyanobenzoic acid |
| BETR-008 | 1129-35-7 | methyl 4-cyanobenzoate |
| BETR-009 | 764659-41-8 | methyl 4-(N,N-dimethylcarbamimidoyl)benzoate |
| BETR-010 | 210963-78-3 | 4-(N,N-dimethylcarbamimidoyl)benzoic acid hydrochloride |
Frequently asked questions
What are the approved indications of Betrixaban?
Approved indications include: Venous thromboembolism, Hepatic function decline, Atrial fibrillation, Atrial flutter, Renal impairment, Thromboembolism.
When does the Betrixaban patent expire?
Based on public sources, the Betrixaban patent expires in 2028.
How many synthesis routes are recorded for Betrixaban?
2 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Betrixaban intermediates?
All intermediates in Betrixaban routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Betrixaban intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29