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Fosfluconazole

Tier C — Watch / trade

Fosfluconazole

Pfizer Inc.
Originator
2003
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:CYP51A1

Brand:Prodif

Indications (approved):Candidiasis, 新型隐球菌感染, Fungal infection

Regional status

US
-
EU
-
China
IND filed
2015-10-15
Japan
Approved
2003-10-16

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield 5.8 g
FOSF-00186386-73-4FOSF-002—API · Fosfluconazole
CodeCAS No.Intermediate
FOSF-00186386-73-42-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
FOSF-002-(dibenzyl-l3-oxidanyl)((2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-yl)oxy)(l1-oxidanyl)phosphine oxide
OptimisedRoute 2Steps 2 · Total yield 359 g
FOSF-002—FOSF-003—API · Fosfluconazole
CodeCAS No.Intermediate
FOSF-002-(dibenzyl-l3-oxidanyl)((2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-yl)oxy)(l1-oxidanyl)phosphine oxide
FOSF-003-di(l5-azanyl) (2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-yl) phosphate

Frequently asked questions

What are the approved indications of Fosfluconazole?

Approved indications include: Candidiasis, 新型隐球菌感染, Fungal infection.

When does the Fosfluconazole patent expire?

No public expiry year is available for Fosfluconazole yet; this page updates once verified.

How many synthesis routes are recorded for Fosfluconazole?

2 synthesis routes are recorded; the shortest is 2 steps with 5.8 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Fosfluconazole intermediates?

All intermediates in Fosfluconazole routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Fosfluconazole intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29