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Zavegepant

Tier C — Watch / trade

Zavegepant

Bristol Myers Squibb
Originator
2023
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:CGRPR

Brand:ZAVZPRET

Indications (approved):Migraine

Regional status

US
Approved
2023-03-09
EU
-
China
Filed / under review
2025-12-04
Japan
-

Factories producing this API1

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

RouteRoute 1Steps 14 · Total yield /
Vazegepant-00179099-07-3Vazegepant-0025927-18-4Vazegepant-003169206-65-9Vazegepant-004175213-46-4Vazegepant-005552-89-6Vazegepant-0061337918-84-9Vazegepant-0071337918-85-0Vazegepant-008855778-84-6Vazegepant-00987-62-7Vazegepant-010138385-59-8Vazegepant-0111676-81-9Vazegepant-01221149-17-7Vazegepant-013855778-38-0Vazegepant-014855778-39-1Vazegepant-015855778-40-4Vazegepant-0162568064-11-7Vazegepant-017928014-64-6Vazegepant-018928014-62-4Vazegepant-01923995-88-2API · Zavegepant
CodeCAS No.Intermediate
Vazegepant-00179099-07-3Availabletert-butyl 4-oxopiperidine-1-carboxylate
Vazegepant-0025927-18-4Availablemethyl 2-(dimethoxyphosphoryl)acetate
Vazegepant-003169206-65-9Availabletert-butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylate
Vazegepant-004175213-46-4Availabletert-butyl 4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate
Vazegepant-005552-89-6Available2-nitrobenzaldehyde
Vazegepant-0061337918-84-9Availabletert-butyl 4-(1-hydroxy-3-methoxy-1-(2-nitrophenyl)-3-oxopropan-2-yl)piperidine-1-carboxylate
Vazegepant-0071337918-85-0Availabletert-butyl 4-(4-hydroxy-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)piperidine-1-carboxylate
Vazegepant-008855778-84-6Available3-(piperidin-4-yl)quinolin-2(1H)-one hydrochloride
Vazegepant-00987-62-7Available2,6-dimethylaniline
Vazegepant-010138385-59-8Available4-iodo-2,6-dimethylaniline hydrochloride
Vazegepant-0111676-81-9Availablemethyl ((benzyloxy)carbonyl)-L-serinate
Vazegepant-01221149-17-7Availablemethyl 2-(((benzyloxy)carbonyl)amino)acrylate
Vazegepant-013855778-38-0Availablemethyl (Z)-3-(4-amino-3,5-dimethylphenyl)-2-(((benzyloxy)carbonyl)amino)acrylate
Vazegepant-014855778-39-1Availablemethyl (R)-3-(4-amino-3,5-dimethylphenyl)-2-(((benzyloxy)carbonyl)amino)propanoate
Vazegepant-015855778-40-4Availablemethyl (R)-2-(((benzyloxy)carbonyl)amino)-3-(7-methyl-1H-indazol-5-yl)propanoate
Vazegepant-0162568064-11-7Availablemethyl (R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate
Vazegepant-017928014-64-6Availablemethyl (R)-3-(7-methyl-1H-indazol-5-yl)-2-(4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamido)propanoate
Vazegepant-018928014-62-4Available(R)-3-(7-methyl-1H-indazol-5-yl)-2-(4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamido)propanoic acid
Vazegepant-01923995-88-2Available1-(1-methylpiperidin-4-yl)piperazine

Frequently asked questions

What are the approved indications of Zavegepant?

Approved indications include: Migraine.

When does the Zavegepant patent expire?

No public expiry year is available for Zavegepant yet; this page updates once verified.

How many synthesis routes are recorded for Zavegepant?

1 synthesis routes are recorded; the shortest is 14 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Zavegepant intermediates?

19 intermediate CAS of Zavegepant are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Zavegepant intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29