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Tedizolid Phosphate

Tier C — Watch / trade

Tedizolid Phosphate · all drugs expiring in 2029 →

Dong-A Pharmaceutical Co., Ltd.
Originator
2014
First approval
2029
Expiry (public)
$0.2B *
Peak sales
Small molecule
Type

Targets:50S ribosomal subunit

Brand:Sivextro

Indications (approved):Skin and skin structure infection, Staphylococcal infection, Bacterial skin disease

Regional status

US
Approved
2014-06-20
EU
Approved
2015-03-23
China
Approved
2019-02-22
Japan
Approved
2018-03-23

Factories producing this API1

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates3 routes

Originator routes × 1Optimised (non-patent) × 2Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 3Steps 7 · Total yield 81.6 mg
Synthetic routes & intermediates Route 3
CodeCAS No.Intermediate
TEDI-005487041-08-7(R)-3-(3-fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-008856866-72-3(R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-01097483-77-7(5-(methylsulfonyl)pyridin-2-yl)methanamine hydrochloride
TEDI-011380380-60-95-bromo-2-(2H-tetrazol-5-yl)pyridine
TEDI-018656-65-54-bromo-3-fluoroaniline
TEDI-019510729-01-8benzyl (4-bromo-3-fluorophenyl)carbamate
TEDI-020874290-59-2(4-(((benzyloxy)carbonyl)amino)-2-fluorophenyl)boronic acid
TEDI-0211220910-89-3benzyl (3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)carbamate
TEDI-0221374651-37-2ammonium 5-(5-bromopyridin-2-yl)tetrazol-2-ide
OptimisedRoute 1Steps 9 · Total yield 815 mg
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
TEDI-001372-19-03-fluoroaniline
TEDI-002149524-47-0benzyl (3-fluorophenyl)carbamate
TEDI-00360456-26-0Available(R)-oxiran-2-ylmethyl butyrate
TEDI-004149524-42-5(R)-3-(3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-005487041-08-7(R)-3-(3-fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-006856867-57-7(R)-3-(3-fluoro-4-(tributylstannyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-007380380-64-35-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine
TEDI-008856866-72-3(R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-009624-28-22,5-dibromopyridine
TEDI-01097483-77-7(5-(methylsulfonyl)pyridin-2-yl)methanamine hydrochloride
TEDI-011380380-60-95-bromo-2-(2H-tetrazol-5-yl)pyridine
OptimisedRoute 2Steps 6 · Total yield 3.82 g
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
TEDI-005487041-08-7(R)-3-(3-fluoro-4-iodophenyl)-5-(hydroxymethyl)oxazolidin-2-one
TEDI-011380380-60-95-bromo-2-(2H-tetrazol-5-yl)pyridine
TEDI-0121261441-79-52-fluoro-1-iodo-4-isocyanatobenzene
TEDI-013113826-06-5(R)-oxiran-2-ylmethyl 4-methylbenzenesulfonate
TEDI-014501939-82-8(R)-(3-(3-fluoro-4-iodophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate
TEDI-0151654754-45-6(R)-(3-(3-fluoro-4-iodophenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate
TEDI-016883231-14-9(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)boronic acid
TEDI-0171654754-39-8dimethyl (6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)boronate

Frequently asked questions

What are the approved indications of Tedizolid Phosphate?

Approved indications include: Skin and skin structure infection, Staphylococcal infection, Bacterial skin disease.

When does the Tedizolid Phosphate patent expire?

Based on public sources, the Tedizolid Phosphate patent expires in 2029.

How many synthesis routes are recorded for Tedizolid Phosphate?

3 synthesis routes are recorded; the shortest is 6 steps with 3.82 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Tedizolid Phosphate intermediates?

1 intermediate CAS of Tedizolid Phosphate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Tedizolid Phosphate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29